Background & Aims: Even though propofol has better recovery profile than traditional
agents, its use is limited because of the perception of increased complication rates. Because …

Background While the complexity of flexible bronchoscopy has increased, standard options
for moderate sedation medications have not changed in three decades. There is a need to …

Background Procedural sedation of ASA III/IV patients has increased risk. Remimazolam (an
ultra-short-acting benzodiazepine) has proven safe and efficient for outpatient colonoscopy …

BACKGROUND: This exploratory study was the first study of remimazolam in patients to
assess the safety and efficacy of different single doses for procedural sedation. METHODS …

Propofol, which is the most commonly used drug for induction of general anaesthesia, has
also become a popular drug for procedural sedation. Because its use may be associated …

BACKGROUND: We performed the first multiple dose study of remimazolam designed to
assess both the feasibility of maintaining suitable sedation during colonoscopy and …

The sedative-hypnotic drugs that do not specifically target the benzodiazepine receptor
belong to a group of agents that depress the CNS in a dose-dependent fashion …

Results: In 2003 sedation was used in 78% of esophagogastroduodenoscopies and
colonoscopies (compared with 60% in 1990), with midazolam being the most commonly …

In this study, we questioned whether propofol provided clinical benefits compared with
midazolam in terms of neuropsychometric recovery, safety profile and patient tolerance …

Aims: To investigate the correlation between centrally assessed human epidermal growth
factor receptor 2 (HER2) immunohistochemistry (IHC) and fluorescence in situ hybridisation …