Twenty-five years ago, the first mammalian Transient Receptor Potential Canonical (TRPC)
channel was cloned, opening the vast horizon of the TRPC field. Today, we know that there …

Perioperative neurocognitive disorder (PND) is a common surgery outcome affecting up to a
third of the elderly patients, and it is associated with high morbidity and increased risk for …

General anesthesia produces multiple side effects. Notably, it temporarily impairs
gastrointestinal motility following surgery and causes the so-called postoperative ileus (POI) …

Recent studies have highlighted the prebiotic effect of inulin through the selective promotion
of colon-residing bacteria, modulation of the composition of the gut microbiome, and …

Oral dosage forms are the preferred solution for systemic treatment and prevention of
disease conditions. However, traditional dosage forms face challenges regarding treatment …

Acetylcholine is the primary excitatory neurotransmitter in visceral smooth muscles, wherein
it binds to and activates two muscarinic receptors subtypes, M 2 and M 3, thus causing …

We compared the effects of two anesthetics, isoflurane and urethane on bladder function in
rats. Arterial pressure, cystometry (CMG), and rhythmic bladder contractions (RBCs) under …

A better understanding of the negative impact of general anesthetics on gastrointestinal
motility requires thorough knowledge of their molecular targets. In this respect the …

Purpose To investigate the impacts of remimazolam tosilate on gastrointestinal hormones
and motility in patients undergoing gastrointestinal endoscopy with sedation. Methods A …

Objective To compare the ease of endoscopic duodenal intubation (EDI) in dogs during
maintenance of general anaesthesia with isoflurane or propofol infusion. Study Design …