Introduction: Effective resuscitation with human albumin solutions is achieved with less fluid
than with crystalloid solutions. However, the role of albumin in today's critical care unit is …

Peripheral and central immune cells are critical for fighting disease, but they can also play a
pivotal role in the onset and/or progression of a variety of neurological conditions that affect …

Targeting single mediators has failed to reduce the mortality of sepsis. We developed a
telodendrimer (TD) nanotrap (NT) to capture various biomolecules via multivalent, hybrid …

Albumin is the most abundant and perhaps most important protein in human blood.
Research has identified many of albumin's possible roles in modulating acid-base balance …

In humans, acid–base balance is crucial to cell homeostasis. Acidosis is observed in
numerous inflammatory processes, primarily acute conditions such as sepsis, trauma, or …

Human serum albumin (HSA) as the most abundant plasma protein carries multifunctional
properties. A major determinant of the efficacy of albumin relies on its potent binding …

Objectives: To assess the impact of the percentage of fluid infused as Lactated Ringer (%
LR) during the first 2 days of ICU admission in hospital mortality and occurrence of acute …

Human immune system has evolved as one of the most powerful defense systems to protect
against invading pathogens and mutated cells. However, when persistent immune …

Background This cohort study compared the prognostic significance of strong ion gap (SIG)
with other acid-base markers in the critically ill. Methods The relationships between SIG …

Crosstalk between molecular regulators miR‐126, hypoxia‐inducible factor 1‐alpha (HIF‐1‐
α), and high‐mobility group box‐1 (HMGB1) contributes to the regulation of inflammation …