Platelet-activating factor acetylhydrolases: an overview and update
N Kono, H Arai - Biochimica et Biophysica Acta (BBA)-Molecular and …, 2019 - Elsevier
Platelet-activating factor acetylhydrolases (PAF-AHs) are unique members of the
phospholipase A 2 family that can hydrolyze the acetyl group of PAF, a signaling …
phospholipase A 2 family that can hydrolyze the acetyl group of PAF, a signaling …
LIS1 controls mitosis and mitotic spindle organization via the LIS1–NDEL1–dynein complex
HM Moon, YH Youn, H Pemble… - Human molecular …, 2014 - academic.oup.com
Heterozygous LIS1 mutations are responsible for the human neuronal migration disorder
lissencephaly. Mitotic functions of LIS1 have been suggested from many organisms …
lissencephaly. Mitotic functions of LIS1 have been suggested from many organisms …
[HTML][HTML] Hepatitis B virus HBx protein mediates the degradation of host restriction factors through the cullin 4 DDB1 E3 ubiquitin ligase complex
The hepatitis B virus (HBV) regulatory HBx protein is required for infection, and its binding to
cellular damaged DNA binding protein 1 (DDB1) is critical for this function. DDB1 is an …
cellular damaged DNA binding protein 1 (DDB1) is critical for this function. DDB1 is an …
Exosomal miR-93-5p from cancer-associated fibroblasts confers malignant phenotypes on bladder cancer cells by targeting PAFAH1B1
X Lu, J Wang, B Dong, L Wang, Y Liu - Anti-Cancer Drugs, 2023 - journals.lww.com
Background Dysregulation of cancer-associated fibroblasts (CAFs) still greatly challenges
the treatments for bladder cancer (BC), where exosomal miRNAs derived from CAFs are one …
the treatments for bladder cancer (BC), where exosomal miRNAs derived from CAFs are one …
[HTML][HTML] MicroRNA-144 suppresses cholangiocarcinoma cell proliferation and invasion through targeting platelet activating factor acetylhydrolase isoform 1b
R Yang, Y Chen, C Tang, H Li, B Wang, Q Yan, J Hu… - Bmc Cancer, 2014 - Springer
Background MicroRNAs are endogenous non-coding RNAs that play important roles in a
wide variety of biological processes such as apoptosis, development, aging and cancer. The …
wide variety of biological processes such as apoptosis, development, aging and cancer. The …
[HTML][HTML] Comprehensive analysis of the prognostic and immunological role of PAFAH1B in pan-cancer
Y Yuan, X Jiang, L Tang, J Wang… - Frontiers in Molecular …, 2022 - frontiersin.org
Platelet-activating factor acetylhydrolase 1B3 (PAFAH1B3) plays a critical role in cancer
initiation, metastasis, and progression; however, it remains unknown how PAFAH1B3 …
initiation, metastasis, and progression; however, it remains unknown how PAFAH1B3 …
Identification of DISE-inducing shRNAs by monitoring cellular responses
M Patel, ME Peter - Cell Cycle, 2018 - Taylor & Francis
Off-target effects (OTE) are an undesired side effect of RNA interference (RNAi) caused by
partial complementarity between the targeting siRNA and mRNAs other than the gene to be …
partial complementarity between the targeting siRNA and mRNAs other than the gene to be …
Discovery of ErbB/HDAC inhibitors by combining the core pharmacophores of HDAC inhibitor vorinostat and kinase inhibitors vandetanib, BMS-690514, neratinib, and …
C Ding, D Li, YW Wang, SS Han, CM Gao… - Chinese Chemical …, 2017 - Elsevier
By combining the core pharmacophores of HDAC inhibitor vorinostat and kinase inhibitors
vandetanib, BMS-690514, neratinib, and TAK-285 with 1, 2, 3-triazole as linker, eight novel …
vandetanib, BMS-690514, neratinib, and TAK-285 with 1, 2, 3-triazole as linker, eight novel …
[HTML][HTML] Hepatic loss of Lissencephaly 1 (Lis1) induces fatty liver and accelerates liver tumorigenesis in mice
The liver is a major organ in lipid metabolism, and its malfunction leads to various diseases.
Nonalcoholic fatty liver disease, the most common chronic liver disorder in developed …
Nonalcoholic fatty liver disease, the most common chronic liver disorder in developed …
[HTML][HTML] MiR-380 inhibits the proliferation and invasion of cholangiocarcinoma cells by silencing LIS1
Z Wei, B Xu, Y Yin, J Chang, Z Li, Y Zhang, X Che… - Cancer Cell …, 2024 - Springer
Background The objective of this study was to determine the role and regulatory mechanism
of miR-380 in cholangiocarcinoma. Methods The TargetScan database and a dual …
of miR-380 in cholangiocarcinoma. Methods The TargetScan database and a dual …