Immunological memory is the basis of protective immunity provided by vaccines and
previous infections. Immunological memory can develop from multiple branches of the …

The past several months have witnessed the emergence of SARS-CoV-2 variants with novel
spike protein mutations that are influencing the epidemiological and clinical aspects of the …

Antibodies against epitopes in S1 give the most accurate CoP against infection by the SARS‐
CoV‐2 coronavirus. Measurement of those antibodies by neutralization or binding assays …

Neutralizing antibodies are known to have a crucial role in protecting against SARS-CoV-2
infection and have been suggested to be a useful correlate of protection for vaccine clinical …

Summary The SARS-CoV-2 Omicron variant has evolved into four sub-lineages—BA. 1, BA.
1.1, BA. 2, and BA. 3—with BA. 2 becoming dominant worldwide. We and others have …

INTRODUCTION Understanding human immune responses to severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) RNA vaccines is of interest for a panoply of reasons …

Emerging evidence indicates that both neutralizing and Fc-mediated effector functions of
antibodies contribute to protection against SARS-CoV-2. It is unclear whether Fc-effector …

Summary The Johnson and Johnson Ad26. COV2. S single-dose vaccine represents an
attractive option for coronavirus disease 2019 (COVID-19) vaccination in countries with …

Antibody-dependent cellular cytotoxicity (ADCC) responses to viral infection are a form of
antibody regulated immune responses mediated through the Fc fragment. Whether severe …

The emergence of SARS-CoV-2 variants and potentially other highly pathogenic
sarbecoviruses in the future highlights the need for pan-sarbecovirus vaccines. Here, we …