Background: Peyronie's disease (PD) is a chronic inflammatory condition affecting adult
males, involving the tunica albuginea of the corpora cavernosa of the penis. PD is frequently …

Atherosclerotic disease is a chronic disease that predominantly affects the elderly and is the
most common cause of cardiovascular death worldwide. Atherosclerosis is closely related to …

The COVID-19 pandemic caused by SARS-CoV-2 virus is an ongoing global health burden.
Severe cases of COVID-19 and the rare cases of COVID-19 vaccine-induced-thrombotic …

Background Potential routes whereby systemic inflammation, oxidative stress and
mitochondrial dysfunction may drive the development of endothelial dysfunction and …

Background Dyslipidemia induces platelet hyperactivation and hyper-aggregation, which
are linked to thrombosis. Anthocyanins could inhibit platelet function in vitro and in mice fed …

As a group of heterodimeric and transmembrane glycoproteins, integrin receptors are widely
expressed in various cell types overall the body. During cardiovascular dysfunction, integrin …

Oxidative stress plays crucial roles in initiating platelet apoptosis that facilitates the
progression of cardiovascular diseases (CVDs). Protocatechuic acid (PCA), a major …

Platelet hyperreactivity and oxidative stress are the important causes of thrombotic disorders
in patients with COVID-19. Oxidative stress, induced by the excessive generation of reactive …

Adiponectin, an adipokine secreted by adipocytes, has anti-atherosclerotic and
antithrombotic activities. AdipoRon is synthetic small molecule adiponectin receptor agonist …

Saponins derived from Panax notoginseng root are widely used as herbal medicines and
dietary supplements due to their wide range of health benefits. However, the effects of those …