Anti-osteoporosis activity of casticin in ovariectomized rats

D Zhang, J Li, X Li, W Liu, Y Yu, H Sun, J Wu… - Toxicology …, 2024 - academic.oup.com
Background Postmenopausal osteoporosis (PMPO) is the most familiar type of osteoporosis,
a silent bone disease. Casticin, a natural flavonoid constituent, improves osteoporosis in …

Petunidin suppresses Hashimoto's thyroiditis by regulating Th1/Th17 homeostasis and oxidative stress

B Liu, L Li, X Wang - Cellular Immunology, 2024 - Elsevier
Hashimoto's thyroiditis (HT) is a prevalent autoimmune thyroid disease, necessitating further
research to identify effective treatment strategies. Two key pathophysiological factors of HT …

Esculentoside A ameliorates DNCB‐induced atopic dermatitis by suppressing the ROS‐NLRP3 axis via activating the Nrf2 pathway

T Liu, Y He, Y Liao - Clinical and Experimental Pharmacology …, 2023 - Wiley Online Library
Atopic dermatitis (AD) is a chronic inflammatory skin condition with a high prevalence.
Inflammation and oxidative stress are strongly associated with AD progression …

ANGPTL2 knockdown induces autophagy to relieve alveolar macrophage pyroptosis by reducing LILRB2‐mediated inhibition of TREM2

F Yang, M Chen, Y Liu, Y Hu, Y Chen… - Journal of Cellular …, 2024 - Wiley Online Library
Acute lung injury (ALI) is featured with a robust inflammatory response. Angiopoietin‐like
protein 2 (ANGPTL2), a pro‐inflammatory protein, is complicated with various disorders …

Dihydromyricetin protects sevoflurane‐induced mitochondrial dysfunction in HT22 hippocampal cells

X Wang, H Li, D Qu - Clinical and Experimental Pharmacology …, 2024 - Wiley Online Library
Sevoflurane (Sev) is a commonly used inhalation anaesthetic that has been shown to cause
hippocampus dysfunction through multiple underlying molecular processes, including …

FBXO28 reduces high-fat diet-induced hyperlipidemia in mice by alleviating abnormal lipid metabolism and inflammatory responses

J Sun, B Du, M Chen, J Jia, X Wang, J Hong - Journal of Endocrinological …, 2024 - Springer
Background Hyperlipidemia is a lipid metabolism disorder with increasing incidence and
prevalence worldwide. Abnormal lipid metabolism and inflammation are two significant …

SRSF3 alleviates ischemic cerebral infarction damage by activating PI3K/Akt pathway

L Cui, S Zhao, H Liu - Developmental neuroscience, 2023 - karger.com
Background: Ischemic cerebral infarction is one of cerebrovascular diseases with high
incidence, disability rate and mortality globally, and neuronal cell apoptosis is a crucial …

[HTML][HTML] Protein inhibitor of activated STAT1 (PIAS1) alleviates cerebral infarction and inflammation after cerebral ischemia in rats

M Wang, P Wang, B Li, G Zhao, N Zhang, R Cao - Heliyon, 2024 - cell.com
Background Ischemic stroke is a severe disorder with high incidence, disability rate and
mortality. Multiple pathogenesis mechanisms are involved in ischemic stroke, such as …

Mesenchymal stem cell-derived exosomal miR-26a induces ferroptosis, suppresses hepatic stellate cell activation, and ameliorates liver fibrosis by modulating …

Y Cao, H Yang, Y Huang, J Lu, H Du, B Wang - Open Medicine, 2024 - degruyter.com
Liver fibrosis is a key contributor to hepatic disease-related mortality. Exosomes derived
from mesenchymal stem cells (MSCs) have been revealed to improve liver fibrosis. To …

[HTML][HTML] Administration of Akebia Saponin D Improved Blood Lipid Levels and Pregnancy Outcomes in Mice with Gestational Diabetes Mellitus

W Chen, J Shi, W Zhang - Balkan Medical Journal, 2023 - ncbi.nlm.nih.gov
Background: Gestational diabetes mellitus (GDM) is a prevalent and severe metabolic
disease in pregnant women that is characterized by a high incidence. Placental oxidative …