Isomorphic Fluorescent Nucleosides
Y Tor - Accounts of Chemical Research, 2024 - ACS Publications
Conspectus In 1960, Weber prophesied that “There are many ways in which the properties
of the excited state can be utilized to study points of ignorance of the structure and function …
of the excited state can be utilized to study points of ignorance of the structure and function …
Nanoparticle‐mediated STING agonist delivery for enhanced cancer immunotherapy
Q Zhou, Y Zhou, T Li, Z Ge - Macromolecular Bioscience, 2021 - Wiley Online Library
Stimulator of interferon genes (STING) are located in the endoplasmic reticulum of cells,
which have been demonstrated to show considerable potentials to achieve efficient …
which have been demonstrated to show considerable potentials to achieve efficient …
Azetidines‐Containing Fluorescent Purine Analogs: Synthesis and Photophysical Properties
K Hadidi, Y Tor - Chemistry–A European Journal, 2022 - Wiley Online Library
Analogues of N, N‐dimethyladenine exploiting both thieno‐and isothiazolo‐pyrimidine
cores were modified with 3‐subsituted azetidines to yield visibly emissive and responsive …
cores were modified with 3‐subsituted azetidines to yield visibly emissive and responsive …
Chemical evolution of cyclic dinucleotides: Perspective of the analogs and their preparation
Z Wang, Z Xi - Tetrahedron, 2021 - Elsevier
Cyclic dinucleotides (CDNs) have been recognized as second messengers in both
prokaryotes and eukaryotes. Until now, four CDNs were identified in the natural organism. In …
prokaryotes and eukaryotes. Until now, four CDNs were identified in the natural organism. In …
Chemical Synthesis of the Fluorescent, Cyclic Dinucleotides cthGAMP
S Veth, A Fuchs, D Özdemir, C Dialer… - …, 2022 - Wiley Online Library
The cGAS‐STING pathway is known for its role in sensing cytosolic DNA introduced by a
viral infection, bacterial invasion or tumorigenesis. Free DNA is recognized by the cyclic …
viral infection, bacterial invasion or tumorigenesis. Free DNA is recognized by the cyclic …
Isomorphic Fluorescent Nucleoside Analogs
KB Steinbuch, Y Tor - Handbook of Chemical Biology of Nucleic Acids, 2023 - Springer
Characterized by their high structural similarity to their native counterparts, yet endowed with
useful photophysical features, isomorphic fluorescent nucleosides present enormous …
useful photophysical features, isomorphic fluorescent nucleosides present enormous …
Cyclic dinucleotide compounds as sting agonists
The disclosure provides cyclic dinucleotides that are useful as STING agonists,
pharmaceutical compositions and vaccines comprising the cyclic dinucleotides, and …
pharmaceutical compositions and vaccines comprising the cyclic dinucleotides, and …