Do Mixed-Species Biofilms Dominate in Chronic Infections?–Need for in situ Visualization of Bacterial Organization

L Kvich, M Burmølle, T Bjarnsholt… - Frontiers in cellular and …, 2020 - frontiersin.org
Chronic infections present a serious economic burden to health-care systems. The severity
and prevalence of chronic infections are continuously increasing due to an aging population …

[HTML][HTML] A review of chemosensors and biosensors for monitoring biofilm dynamics

SC Saccomano, MP Jewell, KJ Cash - Sensors and Actuators Reports, 2021 - Elsevier
Biofilms form complex structures that are ubiquitous in natural environments and can cause
chronic infections which are difficult to treat. While much is known about biofilms, many …

Bacterial aggregates establish at the edges of acute epidermal wounds

L Bay, KN Kragh, SR Eickhardt, SS Poulsen… - Advances in Wound …, 2018 - liebertpub.com
Objective: The bacterial composition and distribution were evaluated in acute standardized
epidermal wounds and uninjured skin by a molecular in situ technology benchmarked to …

Mobile phone ratiometric imaging enables highly sensitive fluorescence lateral flow immunoassays without external optical filters

KG Shah, V Singh, PC Kauffman, K Abe… - Analytical …, 2018 - ACS Publications
Paper-based diagnostic tests based on the lateral flow immunoassay concept promise low-
cost, point-of-care detection of infectious diseases, but such assays suffer from poor limits of …

Bacterial biofilms: a possible mechanism for chronic infection in patients with lumbar disc herniation – a prospective proof‐of‐concept study using fluorescence in situ …

S Ohrt‐Nissen, BG Fritz, J Walbom, KN Kragh… - Apmis, 2018 - Wiley Online Library
A relationship has been suggested between lumbar disc herniation (LDH) and chronic
bacterial infection frequently involving Propionibacterium acnes, which is known to cause …

The discovery of bacterial biofilm in patients with muscle invasive bladder cancer

N Nadler, L Kvich, T Bjarnsholt, JB Jensen, I Gögenur… - Apmis, 2021 - Wiley Online Library
The carcinogenic effects of microorganisms have been discovered in multiple cancer types.
In urology, the development of squamous cell carcinoma of the bladder due to the parasitic …

Formation and emergent dynamics of spatially organized microbial systems

K Cremin, SJN Duxbury, J Rosko… - Interface …, 2023 - royalsocietypublishing.org
Spatial organization is the norm rather than the exception in the microbial world. While the
study of microbial physiology has been dominated by studies in well-mixed cultures, there is …

The role of biofilm in chronic laryngitis and in head and neck cancer

TJ Kinnari - Current opinion in otolaryngology & head and neck …, 2015 - journals.lww.com
The role of biofilm in chronic laryngitis and in head and ne... : Current Opinion in
Otolaryngology & Head and Neck Surgery The role of biofilm in chronic laryngitis and in head …

Bacterial biofilm formation inside colonic crypts may accelerate colorectal carcinogenesis

H Raskov, KN Kragh, T Bjarnsholt, M Alamili… - Clinical and translational …, 2018 - Springer
Background Research in the field of relation between microbes and colorectal
carcinogenesis has gained increasing interest in past years. Recently, link between …

Quality control in diagnostic fluorescence in situ hybridization (FISH) in microbiology

J Kikhney, A Moter - Fluorescence in-situ hybridization (FISH) for microbial …, 2021 - Springer
This overview addresses fluorescence in situ hybridization (FISH) in a diagnostic
microbiology setting with its associated problems and pitfalls and how to control them, but …