Ionic liquids as tool to improve enzymatic organic synthesis

T Itoh - Chemical Reviews, 2017 - ACS Publications
Ionic liquids (ILs) have now been acknowledged as reaction media for biotransformations.
The first three examples were reported in this field in 2000, and since then, numerous …

Protein stabilization and enzyme activation in ionic liquids: specific ion effects

H Zhao - Journal of Chemical Technology & Biotechnology, 2016 - Wiley Online Library
There are still debates on whether the hydration of ions perturbs the water structure, and
what is the degree of such disturbance; therefore, the origin of the Hofmeister effect on …

Enzymatic reductions for the chemist

F Hollmann, IWCE Arends, D Holtmann - Green Chemistry, 2011 - pubs.rsc.org
When challenged by a difficult reduction reaction, a chemist should always also consider
biocatalysis in synthesis planning. The inherent selectivity of enzymes has been known for …

Recent advances in the applications of ionic liquids in protein stability and activity: a review

R Patel, M Kumari, AB Khan - Applied biochemistry and biotechnology, 2014 - Springer
Room temperatures ionic liquids are considered as miraculous solvents for biological
system. Due to their inimitable properties and large variety of applications, they have been …

Hofmeister effects: an explanation for the impact of ionic liquids on biocatalysis

Z Yang - Journal of biotechnology, 2009 - Elsevier
Ionic liquids (ILs) have shown potentials as a new reaction medium for biocatalysis, either as
such or as an aqueous mixture. Their unique ionic nature is important in affecting the …

Proteins in ionic liquids: Reactions, applications, and futures

A Schindl, ML Hagen, S Muzammal… - Frontiers in …, 2019 - frontiersin.org
Biopolymer processing and handling is greatly facilitated by the use of ionic liquids, given
the increased solubility, and in some cases, structural stability imparted to these molecules …

Toward advanced ionic liquids. Polar, enzyme-friendly solvents for biocatalysis

J Gorke, F Srienc, R Kazlauskas - Biotechnology and Bioprocess …, 2010 - Springer
Ionic liquids, also called molten salts, are mixtures of cations and anions that melt below
100° C. Typical ionic liquids are dialkylimidazolium cations with weakly coordinating anions …

Biocatalysis in ionic liquids: state-of-the-union

RA Sheldon - Green Chemistry, 2021 - pubs.rsc.org
This perspective reviews the current status and prospects of biocatalysis in ionic liquids.
Although they are not strictly speaking ionic liquids, deep eutectic solvents are included …

What do we learn from enzyme behaviors in organic solvents?–Structural functionalization of ionic liquids for enzyme activation and stabilization

H Zhao - Biotechnology Advances, 2020 - Elsevier
Enzyme activity in nonaqueous media (eg conventional organic solvents) is typically lower
than in water by several orders of magnitude. There is a rising interest of developing new …

Ionic Liquids in Metal, Photo-, Electro-, and (Bio) Catalysis

J Dupont, BC Leal, P Lozano, AL Monteiro… - Chemical …, 2024 - ACS Publications
Ionic liquids (ILs) have unique physicochemical properties that make them advantageous for
catalysis, such as low vapor pressure, non-flammability, high thermal and chemical …