Chagas disease, caused by the protozoan Trypanosoma cruzi, is a lifelong and debilitating
illness of major significance throughout Latin America and an emergent threat to global …

Diagnosis of individuals infected by Trypanosoma cruzi is performed mainly by serological
tests using crude antigens, which might crossreact with other infections. In the past ten …

A rapid serologic test for diagnosis of T. cruzi infection (Chagas Stat Pak) was developed
using recombinant proteins in an immunochromatographic assay. This cassette format test …

The aim of this work was to determine the best strategy to display antigens (Ags) on
immunochemical devices to improve test selectivity and sensitivity. We comparatively …

Chagas Disease, caused by the protozoan Trypanosoma cruzi, is a major health and
economic problem in Latin America for which no vaccine or appropriate drugs for large …

Background Chagas disease (CD) is caused by Trypanosoma cruzi. The chronic phase of
CD is characterized by the presence of IgG anti-T. cruzi antibodies; and diagnosis is …

Chimeric T. cruzi antigens have been proposed as a diagnostic tool for chronic Chagas
disease (CD) in both settings where Chagas disease is endemic and those where it is not …

The performance of serologic tests in chronic Chagas disease diagnosis largely depends on
the type and quality of the antigen preparations that are used for detection of anti …

Background Chagas disease (CD) is caused by Trypanosoma cruzi, which is transmitted
mainly through the feces/urine of infected triatomine bugs. The acute phase lasts 2–3 …

Chagas' disease is caused by the protozoan parasite Trypanosoma cruzi and is one of the
most important endemic problems in Latin America. Lately, it has also become a health …