Phytochemicals represent a large and diverse group of naturally occurring compounds,
bioactive nutrients, or phytonutrients produced by plants, widely found in fruits, vegetables …

Mast cells (MCs) are evolutionarily ancient innate immune cells with important roles in
protective immunity against bacteria, parasites, and venomous animals. They can be found …

Background Lebrikizumab is a novel, high-affinity monoclonal antibody that selectively binds
to interleukin (IL)-13. Objectives To evaluate the efficacy and safety of lebrikizumab …

Atopic dermatitis (AD) is a chronic skin disease caused by skin immune dyshomeostasis and
accompanied by severe pruritus. Although oxidative stress and mechanical scratching can …

Atopic dermatitis (AD) is a chronic inflammatory skin condition increasing in industrial
nations at a pace that suggests environmental drivers. We hypothesize that the dysbiosis …

Abstract Background Atopic Dermatitis (AD) is a highly pruritic, chronic-recurrent
inflammatory skin condition associated with erythematous lesions that affect a significant …

Atopic dermatitis (AD) and chronic urticaria (CU) are common skin diseases with an
increasing prevalence and pathogenesis that are not fully understood. Emerging evidence …

Atopic Dermatitis (AD) is an extremely pruritic inflammatory skin disease that has a
worldwide prevalence of approximately 2.69%, with significant variability by country. 1 In the …

Atopic dermatitis (AD) is a common chronic inflammatory skin disease with a high
prevalence worldwide, including countries from Asia, Africa, and Latin America, and in …

The NLRP3 inflammasome is upregulated by various agents, such as nuclear factor-kappa
B (NF-κB), lipopolysaccharide (LPS), and adenosine triphosphate (ATP). The NLRP3 …