Statin use for the primary prevention of cardiovascular disease in adults: updated evidence report and systematic review for the US Preventive Services Task Force

R Chou, A Cantor, T Dana, J Wagner, AY Ahmed, R Fu… - Jama, 2022 - jamanetwork.com
Importance A 2016 review for the US Preventive Services Task Force (USPSTF) found use
of statins for primary prevention of cardiovascular disease (CVD) was associated with …

Statins for prevention of cardiovascular disease in adults: evidence report and systematic review for the US Preventive Services Task Force

R Chou, T Dana, I Blazina, M Daeges, TL Jeanne - Jama, 2016 - jamanetwork.com
Importance Cardiovascular disease (CVD), the leading cause of mortality and morbidity in
the United States, may be potentially preventable with statin therapy. Objective To …

Long-term efficacy and safety of moderate-intensity statin with ezetimibe combination therapy versus high-intensity statin monotherapy in patients with atherosclerotic …

BK Kim, SJ Hong, YJ Lee, SJ Hong, KH Yun, BK Hong… - The Lancet, 2022 - thelancet.com
Background Drug combinations rather than increasing doses of one drug can achieve
greater efficacy and lower risks. Thus, as an alternative to high-intensity statin monotherapy …

Changes in prescription and over-the-counter medication and dietary supplement use among older adults in the United States, 2005 vs 2011

DM Qato, J Wilder, LP Schumm, V Gillet… - JAMA internal …, 2016 - jamanetwork.com
Importance Prescription and over-the-counter medicines and dietary supplements are
commonly used, alone and together, among older adults. However, the effect of recent …

Effects of statin therapy on coronary artery plaque volume and high-risk plaque morphology in HIV-infected patients with subclinical atherosclerosis: a randomised …

J Lo, MT Lu, EJ Ihenachor, J Wei, SE Looby… - The lancet HIV, 2015 - thelancet.com
Background HIV-infected patients have a high risk of myocardial infarction. We aimed to
assess the ability of statin treatment to reduce arterial inflammation and achieve regression …

The diabetogenic action of statins—mechanisms and clinical implications

DJ Betteridge, R Carmena - Nature Reviews Endocrinology, 2016 - nature.com
Abstract Treatment with statins has transformed primary and secondary prevention of
cardiovascular disease (CVD), including thrombotic stroke. Evidence-based data …

Moderate-intensity statin with ezetimibe vs. high-intensity statin in patients with diabetes and atherosclerotic cardiovascular disease in the RACING trial

YJ Lee, JY Cho, SC You, YH Lee, KH Yun… - European heart …, 2023 - academic.oup.com
Aims This study evaluated the effect of moderate-intensity statin with ezetimibe combination
therapy vs. high-intensity statin monotherapy among patients with diabetes mellitus (DM) …

Hypothyroidism is a risk factor for new-onset diabetes: a cohort study

N Gronich, SN Deftereos, I Lavi, AS Persidis… - Diabetes …, 2015 - Am Diabetes Assoc
OBJECTIVE To identify risk factors for the development of statin-associated diabetes mellitus
(DM). RESEARCH DESIGN AND METHODS The study was conducted in two phases …

[HTML][HTML] Network meta-analysis incorporating randomized controlled trials and non-randomized comparative cohort studies for assessing the safety and effectiveness …

C Cameron, B Fireman, B Hutton, T Clifford, D Coyle… - Systematic reviews, 2015 - Springer
Network meta-analysis is increasingly used to allow comparison of multiple treatment
alternatives simultaneously, some of which may not have been compared directly in primary …

Adverse effects of statins-myths and reality

I Simic, Z Reiner - Current pharmaceutical design, 2015 - ingentaconnect.com
Statins reduce cardiovascular mortality and morbidity as well as cardiovascular events in
patients with a very high risk of cardiovascular disease (CVD) and also in subjects with high …