Thyroid-related adverse events induced by immune checkpoint inhibitors
Immune checkpoint inhibitors, namely anti-CTLA-4, anti-PD-1 and anti-PD-L1 monoclonal
antibodies, have emerged in the last decade as a novel form of cancer treatment, promoting …
antibodies, have emerged in the last decade as a novel form of cancer treatment, promoting …
Immune checkpoint inhibitors-related thyroid dysfunction: epidemiology, clinical presentation, possible pathogenesis, and management
L Zhan, H Feng, H Liu, L Guo, C Chen… - Frontiers in …, 2021 - frontiersin.org
Immune checkpoint inhibitors (ICIs) are a group of drugs employed in the treatment of
various types of malignant tumors and improve the therapeutic effect. ICIs blocks negative co …
various types of malignant tumors and improve the therapeutic effect. ICIs blocks negative co …
Novel HLA-DRB1 alleles contribute risk for disease susceptibility in primary biliary cholangitis
Y Li, X Liu, Y Wang, Y Zhou, S Hu, H Yang… - Digestive and Liver …, 2022 - Elsevier
Background Primary biliary cholangitis (PBC) is a complex disease with high heritability. We
investigated the association between human leukocyte antigen (HLA)-DRB1 alleles and …
investigated the association between human leukocyte antigen (HLA)-DRB1 alleles and …
Pervasive additive and non-additive effects within the HLA region contribute to disease risk in the UK Biobank
The human leukocyte antigen (HLA) region is one of the most disease-associated regions of
the human genome, yet even well-studied alleles in the HLA region have unknown impact …
the human genome, yet even well-studied alleles in the HLA region have unknown impact …
Mayan alleles of the HLA-DRB1 major histocompatibility complex might contribute to the genetic susceptibility to systemic lupus erythematosus in Mexican patients …
R Garcia-Silva, S Hernandez-Doño… - Clinical …, 2021 - Springer
Introduction Systemic lupus erythematosus (SLE) is the prototypic autoimmune disease that
disrupts numerous immunity mechanisms with the potential to exert damage to any organ or …
disrupts numerous immunity mechanisms with the potential to exert damage to any organ or …