Parkinson's disease (PD) is known to affect the brain motor circuits involving the basal
ganglia (BG) and to induce, among other signs, general slowness and paucity of …

In the last decades, clinical neuroscience found a novel ally in neurotechnologies, devices
able to record and stimulate electrical activity in the nervous system. These technologies …

Background Speech impairment is commonly reported in Parkinson's disease and is not
consistently improved by available therapies–including deep brain stimulation of the …

Motor symptoms of Parkinson's Disease (PD) are associated with dopamine deficits and
pathological oscillation of basal ganglia (BG) neurons in the β range ([12-30] Hz). However …

A brain-machine interface represents a promising therapeutic avenue for the treatment of
many neurologic conditions. Deep brain stimulation (DBS) is an invasive, neuro-modulatory …

Contemporary Clinical Neurosciences bridges the gap between bench research in the
neurosciences and clinical neurology work by offering translational research on all aspects …

Tremor is one of the most common neurological symptoms. Its clinical and neurobiological
complexity necessitates novel approaches for granular phenotyping. Instrumented …

Abstract Analysis of coupling between the phases and amplitudes of neural oscillations has
gained increasing attention as an important mechanism for large-scale brain network …

We present the clinical data and subthalamic recordings of a patient with Parkinson's
disease treated for one year with adaptive deep brain stimulation (aDBS). This novel …

Objective. Cortical function is under constant modulation by internally-driven, latent
variables that regulate excitability, collectively known as' cortical state'. Despite a vast …