Stress, serotonin, and hippocampal neurogenesis in relation to depression and antidepressant effects

I Mahar, FR Bambico, N Mechawar… - … & Biobehavioral Reviews, 2014 - Elsevier
Chronic stressful life events are risk factors for developing major depression, the
pathophysiology of which is strongly linked to impairments in serotonin (5-HT) …

The neurobiology of anhedonia and other reward-related deficits

A Der-Avakian, A Markou - Trends in neurosciences, 2012 - cell.com
Anhedonia, or markedly diminished interest or pleasure, is a hallmark symptom of major
depression, schizophrenia and other neuropsychiatric disorders. Over the past three …

Is serotonin an upper or a downer? The evolution of the serotonergic system and its role in depression and the antidepressant response

PW Andrews, A Bharwani, KR Lee, M Fox… - Neuroscience & …, 2015 - Elsevier
The role of serotonin in depression and antidepressant treatment remains unresolved
despite decades of research. In this paper, we make three major claims. First, serotonin …

Animal models of depression: molecular perspectives

V Krishnan, EJ Nestler - Molecular and functional models in …, 2011 - Springer
Much of the current understanding about the pathogenesis of altered mood, impaired
concentration and neurovegetative symptoms in major depression has come from animal …

Sex differences in animal models of psychiatric disorders

N Kokras, C Dalla - British journal of pharmacology, 2014 - Wiley Online Library
Psychiatric disorders are characterized by sex differences in their prevalence,
symptomatology and treatment response. Animal models have been widely employed for …

The role of serotonin in drug use and addiction

CP Müller, JR Homberg - Behavioural brain research, 2015 - Elsevier
The use of psychoactive drugs is a wide spread behaviour in human societies. The
systematic use of a drug requires the establishment of different drug use-associated …

A critical review of sex differences in decision-making tasks: Focus on the Iowa Gambling Task

R van den Bos, J Homberg, L de Visser - Behavioural brain research, 2013 - Elsevier
It has been observed that men and women show performance differences in the Iowa
Gambling Task (IGT), a task of decision-making in which subjects through exploration learn …

A scientometrics analysis and visualization of depressive disorder

D Xu, YL Wang, KT Wang, Y Wang… - Current …, 2021 - ingentaconnect.com
Multiple studies on the pathomechanisms of depressive disorder and antidepressants have
been reported. However, literature involving scientometric analysis of depressive disorder is …

P5-HT1A receptors in mood and anxiety: recent insights into autoreceptor versus heteroreceptor function

AL Garcia-Garcia, A Newman-Tancredi… - …, 2014 - Springer
Abstract Rationale Serotonin (5-HT) neurotransmission is intimately linked to anxiety and
depression and a diverse body of evidence supports the involvement of the main inhibitory …

The reciprocal interaction between serotonin and social behaviour

D Kiser, B SteemerS, I Branchi, JR Homberg - … & Biobehavioral Reviews, 2012 - Elsevier
Serotonin (5-HT) is an ancient molecule directing behavioural responses to environmental
stimuli. The social environment is the most powerful environmental factor. It is well …