Recently, mechanical milling using a mixer mill or planetary mill has been fruitfully utilized in
organic synthesis under solvent-free conditions. This review article provides a …

We provide a brief overview of recent advances in the use of mechanochemical techniques
for the synthesis of organic molecules and materials, highlighting selected examples of …

The reaction of ninhydrin with primary amino groups to form the purple dye now called
Ruhemann's purple (RP) was discovered by Siegfried Ruhemann in 1910. In addition …

Mechanochemistry provides a method to reduce or eliminate the use of solvents by carrying
out reactions through the grinding of neat reagents. Until recently a significant drawback of …

Mechanochemistry means mechanical breakage of intramolecular bonds by external force
and must be differentiated from molecular solid-state chemistry, where contacts between …

The two-volume Encyclopedia of Supramolecular Chemistry offers authoritative, centralized
information on a rapidly expanding interdisciplinary field. User-friendly and high-quality …

Although isocyanide‐based multicomponent reactions (MCRs), introduced in 1921 by
Passerini, largely predominate nowadays in the construction of widely diverse heterocycles …

Ball milling has been applied in numerous solvent‐free carbon‐carbon bond formations. In
many cases, these transformations proved superior to the analogous reactions performed in …

Recently, chemical reactions induced or facilitated by mechanical energy have gained
recognition in diverse areas of chemical synthesis. In particular, mechanosyntheses of …

Numerous Knoevenagel condensations of solid or liquid aromatic aldehydes are performed
with four barbituric acids, Meldrum's acid, dimedone, cyanoacetamide, malodinitrile and …