Electrode materials in modern organic electrochemistry

DM Heard, AJJ Lennox - Angewandte Chemie International …, 2020 - Wiley Online Library
The choice of electrode material is critical for achieving optimal yields and selectivity in
synthetic organic electrochemistry. The material imparts significant influence on the kinetics …

Electrochemical strategies for C–H functionalization and C–N bond formation

MD Kärkäs - Chemical Society Reviews, 2018 - pubs.rsc.org
Conventional methods for carrying out carbon–hydrogen functionalization and carbon–
nitrogen bond formation are typically conducted at elevated temperatures, and rely on …

Electrocatalytic C–H Activation

N Sauermann, TH Meyer, Y Qiu, L Ackermann - Acs Catalysis, 2018 - ACS Publications
C–H activation has emerged as a transformative tool in molecular synthesis, but until
recently oxidative C–H activations have largely involved the use of stoichiometric amounts of …

Chemoselective electrosynthesis using rapid alternating polarity

Y Kawamata, K Hayashi, E Carlson… - Journal of the …, 2021 - ACS Publications
Challenges in the selective manipulation of functional groups (chemoselectivity) in organic
synthesis have historically been overcome either by using reagents/catalysts that tunably …

Direct electrochemical defluorinative carboxylation of α-CF 3 alkenes with carbon dioxide

XT Gao, Z Zhang, X Wang, JS Tian, SL Xie, F Zhou… - Chemical …, 2020 - pubs.rsc.org
An unprecedented γ-carboxylation of α-CF3 alkenes with CO2 is reported. This approach
constitutes a rare example of using electrochemical methods to achieve regioselectivity …

Green electrosynthesis of drug metabolites

R Asra, AM Jones - Toxicology Research, 2023 - academic.oup.com
In this concise review, the field of electrosynthesis (ES) as a green methodology for
understanding drug metabolites linked to toxicology is exemplified. ES describes the …

Electrochemical behavior and voltammetric determination of two synthetic aroyl amides opioids

A Capucciati, A Burato, C Bersani, S Protti, A Profumo… - Chemosensors, 2023 - mdpi.com
In the present work, we describe the electrochemical behaviour of two opioids structurally
related to aroyl amides of forensic interest, namely U-47700 and AH-7921. The data …

Amino acids in electrochemical metal-free benzylic CH amidation

S Strekalova, A Kononov, Y Budnikova - Tetrahedron Letters, 2022 - Elsevier
This report describes the mild electrochemical metal-, oxidant-, additive-free site-selective
direct Csingle bond H amidation of benzyl C (sp 3)-H bonds in an undivided cell using α …

Electrochemical Scaled‐up Synthesis of Cyclic Enecarbamates as Starting Materials for Medicinal Chemistry Relevant Building Bocks

OD Tereshchenko, MY Perebiynis… - Advanced Synthesis …, 2020 - Wiley Online Library
The electrochemical Shono oxidation of Boc‐protected cyclic amines was revised. The
conditions for scalable electrochemical synthesis of cyclic enecarbamates were found. The …

Metabolism mimicry: an electrosynthetic method for the selective deethylation of tertiary benzamides

MK Bal, CE Banks, AM Jones - ChemElectroChem, 2019 - Wiley Online Library
The electrosynthetic deethylation of tertiary amides, commonly encountered moieties in
pharmaceuticals and agrochemicals, is an analogue of the function of cytochrome P450 …