Antimicrobial host defence peptides: functions and clinical potential
Cationic host defence peptides (CHDP), also known as antimicrobial peptides, are naturally
occurring peptides that can combat infections through their direct microbicidal properties …
occurring peptides that can combat infections through their direct microbicidal properties …
Functional role of dendritic cell subsets in cancer progression and clinical implications
A Del Prete, F Sozio, I Barbazza, V Salvi… - International journal of …, 2020 - mdpi.com
Dendritic cells (DCs) constitute a complex network of cell subsets with common functions but
also with many divergent aspects. All dendritic cell subsets share the ability to prime T cell …
also with many divergent aspects. All dendritic cell subsets share the ability to prime T cell …
[HTML][HTML] Antimicrobial peptides and the gut microbiome in inflammatory bowel disease
J Gubatan, DR Holman, CJ Puntasecca… - World Journal of …, 2021 - ncbi.nlm.nih.gov
Antimicrobial peptides (AMP) are highly diverse and dynamic molecules that are expressed
by specific intestinal epithelial cells, Paneth cells, as well as immune cells in the …
by specific intestinal epithelial cells, Paneth cells, as well as immune cells in the …
The neutrophil antimicrobial peptide cathelicidin promotes Th17 differentiation
D Minns, KJ Smith, V Alessandrini, G Hardisty… - Nature …, 2021 - nature.com
The host defence peptide cathelicidin (LL-37 in humans, mCRAMP in mice) is released from
neutrophils by de-granulation, NETosis and necrotic death; it has potent anti-pathogen …
neutrophils by de-granulation, NETosis and necrotic death; it has potent anti-pathogen …
A Nanovaccine Based on Adjuvant Peptide FK‐13 and l‐Phenylalanine Poly(ester amide) Enhances CD8+ T Cell‐Mediated Antitumor Immunity
C Xie, X You, H Zhang, J Li, L Wang, Y Liu… - Advanced …, 2023 - Wiley Online Library
Cancer vaccines have shown promise as effective means of antitumor immunotherapy by
inducing tumor antigen‐specific T cell immunity. In this study, a novel peptide‐based tumor …
inducing tumor antigen‐specific T cell immunity. In this study, a novel peptide‐based tumor …
The human cathelicidin peptide LL-37 inhibits pancreatic cancer growth by suppressing autophagy and reprogramming of the tumor immune microenvironment
Z Zhang, WQ Chen, SQ Zhang, JX Bai… - Frontiers in …, 2022 - frontiersin.org
Pancreatic cancer is amongst the most lethal malignancies, while its poor prognosis could
be associated with promotion of autophagy and the tumor immune microenvironment …
be associated with promotion of autophagy and the tumor immune microenvironment …
Drug resistance: An incessant fight against evolutionary strategies of survival
F Ramos-Martín, N D'amelio - Microbiology Research, 2023 - mdpi.com
The inherent capacity of all organisms to evolve under selective pressure has created
multidrug-resistant microbes and cells that are now threatening decades of progress in …
multidrug-resistant microbes and cells that are now threatening decades of progress in …
Immunomodulatory significance of natural peptides in mammalians: Promising agents for medical application
Modulation of immune responses by immunoregulatory agents, such as the natural or
synthetic immunomodulatory peptides, has been suggested as a potential strategy to …
synthetic immunomodulatory peptides, has been suggested as a potential strategy to …
Host defense peptides as immunomodulators: The other side of the coin
EM Martell, M Gonzalez-Garcia, L Ständker… - Peptides, 2021 - Elsevier
Host defense peptides (HDPs) exhibit a broad range of antimicrobial and
immunomodulatory activities. In this sense, both functions are like different sides of the same …
immunomodulatory activities. In this sense, both functions are like different sides of the same …
[HTML][HTML] Non-toxic antimicrobial peptide Hm-AMP2 from leech metagenome proteins identified by the gradient-boosting approach
EN Grafskaia, ER Pavlova, IA Latsis, MV Malakhova… - Materials & Design, 2022 - Elsevier
The number of infections caused by antibiotic-resistant pathogens is increasing alarmingly
every year and will continue to grow. Antimicrobial peptides (AMPs) are considered new …
every year and will continue to grow. Antimicrobial peptides (AMPs) are considered new …