[HTML][HTML] Timing of lifespan influences on brain and cognition

KB Walhovd, M Lövden, AM Fjell - Trends in cognitive sciences, 2023 - cell.com
Modifiable risk and protective factors for boosting brain and cognitive development and
preventing neurodegeneration and cognitive decline are embraced in neuroimaging …

Brain aerobic glycolysis and resilience in Alzheimer disease

MS Goyal, T Blazey, NV Metcalf… - Proceedings of the …, 2023 - National Acad Sciences
The distribution of brain aerobic glycolysis (AG) in normal young adults correlates spatially
with amyloid-beta (Aβ) deposition in individuals with symptomatic and preclinical Alzheimer …

[HTML][HTML] Alzheimer's disease risk biomarkers: progress and challenges

PB Adkins-Jackson, DW Belsky - The Lancet Healthy Longevity, 2022 - thelancet.com
Alzheimer's disease and Alzheimer's disease-related dementias (AD–ADRD) are
progressive neurodegenerative conditions that occur more frequently in older adults. As …

Biological brain age prediction using machine learning on structural neuroimaging data: Multi-cohort validation against biomarkers of Alzheimer's Disease and …

I Cumplido-Mayoral, M García-Prat, G Operto, C Falcon… - Elife, 2023 - elifesciences.org
Brain-age can be inferred from structural neuroimaging and compared to chronological age
(brain-age delta) as a marker of biological brain aging. Accelerated aging has been found in …

[HTML][HTML] Advanced structural brain aging in preclinical autosomal dominant Alzheimer disease

PR Millar, BA Gordon, JK Wisch, SA Schultz… - Molecular …, 2023 - Springer
Background “Brain-predicted age” estimates biological age from complex, nonlinear
features in neuroimaging scans. The brain age gap (BAG) between predicted and …

Considerations on brain age predictions from repeatedly sampled data across time

M Korbmacher, MY Wang, R Eikeland… - Brain and …, 2023 - Wiley Online Library
Introduction Brain age, the estimation of a person's age from magnetic resonance imaging
(MRI) parameters, has been used as a general indicator of health. The marker requires …

[HTML][HTML] Fetal influence on the human brain through the lifespan

KB Walhovd, SK Krogsrud, IK Amlien, Ø Sørensen… - Elife, 2024 - elifesciences.org
Human fetal development has been associated with brain health at later stages. It is
unknown whether growth in utero, as indexed by birth weight (BW), relates consistently to …

[HTML][HTML] Report of the Medical Image De-Identification (MIDI) Task Group-Best Practices and Recommendations

DA Clunie, A Flanders, A Taylor, B Erickson, B Bialecki… - Arxiv, 2023 - ncbi.nlm.nih.gov
1.4 Support This project has been funded in whole or in part with Federal funds from the
National Cancer Institute, National Institutes of Health, under Contract No …

[HTML][HTML] Brain age as a biomarker for pathological versus healthy ageing–a REMEMBER study

MMJ Wittens, S Denissen, DM Sima, E Fransen… - Alzheimer's Research & …, 2024 - Springer
Objectives This study aimed to evaluate the potential clinical value of a new brain age
prediction model as a single interpretable variable representing the condition of our brain …

[HTML][HTML] Why is iron deficiency/anemia linked to Alzheimer's disease and its comorbidities, and how is it prevented?

K Fehsel - Biomedicines, 2023 - mdpi.com
Impaired iron metabolism has been increasingly observed in many diseases, but a deeper,
mechanistic understanding of the cellular impact of altered iron metabolism is still lacking. In …