Pseudomonas aeruginosa: pathogenesis, virulence factors, antibiotic resistance, interaction with host, technology advances and emerging therapeutics

S Qin, W Xiao, C Zhou, Q Pu, X Deng, L Lan… - Signal transduction and …, 2022 - nature.com
Pseudomonas aeruginosa (P. aeruginosa) is a Gram-negative opportunistic pathogen that
infects patients with cystic fibrosis, burn wounds, immunodeficiency, chronic obstructive …

Bacterial antibiotic resistance: the most critical pathogens

G Mancuso, A Midiri, E Gerace, C Biondo - Pathogens, 2021 - mdpi.com
Antibiotics have made it possible to treat bacterial infections such as meningitis and
bacteraemia that, prior to their introduction, were untreatable and consequently fatal …

Pseudomonas aeruginosa: Infections, Animal Modeling, and Therapeutics

SJ Wood, TM Kuzel, SH Shafikhani - Cells, 2023 - mdpi.com
Pseudomonas aeruginosa is an important Gram-negative opportunistic pathogen which
causes many severe acute and chronic infections with high morbidity, and mortality rates as …

[HTML][HTML] Clinical data from studies involving novel antibiotics to treat multidrug-resistant Gram-negative bacterial infections

SS Kanj, M Bassetti, P Kiratisin, C Rodrigues… - International journal of …, 2022 - Elsevier
Abstract Multidrug-resistant (MDR) Gram-negative bacteria (GNB) pose a critical threat to
global healthcare, worsening outcomes and increasing mortality among infected patients …

A review of chemical signaling pathways in the quorum sensing circuit of Pseudomonas aeruginosa

K Vadakkan, AK Ngangbam, K Sathishkumar… - International Journal of …, 2024 - Elsevier
Pseudomonas aeruginosa, an increasingly common competitive and biofilm organism in
healthcare infection with sophisticated, interlinked and hierarchic quorum systems (Las, Rhl …

Roles of Two-Component Systems in Pseudomonas aeruginosa Virulence

M Sultan, R Arya, KK Kim - International journal of molecular sciences, 2021 - mdpi.com
Pseudomonas aeruginosa is an opportunistic pathogen that synthesizes and secretes a
wide range of virulence factors. P. aeruginosa poses a potential threat to human health …

Pseudomonas aeruginosa: A typical biofilm forming pathogen and an emerging but underestimated pathogen in food processing

X Li, N Gu, TY Huang, F Zhong, G Peng - Frontiers in Microbiology, 2023 - frontiersin.org
Pseudomonas aeruginosa (P. aeruginosa) is a notorious gram-negative pathogenic
microorganism, because of several virulence factors, biofilm forming capability, as well as …

Pseudomonas aeruginosa: Recent Advances in Vaccine Development

M Killough, AM Rodgers, RJ Ingram - Vaccines, 2022 - mdpi.com
Pseudomonas aeruginosa is an important opportunistic human pathogen. Using its arsenal
of virulence factors and its intrinsic ability to adapt to new environments, P. aeruginosa …

[HTML][HTML] Pseudomonas aeruginosa: an antibiotic resilient pathogen with environmental origin

P Laborda, F Sanz-García, S Hernando-Amado… - Current Opinion in …, 2021 - Elsevier
Highlights•P. aeruginosa is opportunistic pathogen with an environmental origin.•P.
aeruginosa presents low susceptibility to currently used antibiotics.•P. aeruginosa displays a …

Immunization with lytic polysaccharide monooxygenase CbpD induces protective immunity against Pseudomonas aeruginosa pneumonia

F Askarian, CM Tsai, G Cordara… - Proceedings of the …, 2023 - National Acad Sciences
Pseudomonas aeruginosa (PA) CbpD belongs to the lytic polysaccharide monooxygenases
(LPMOs), a family of enzymes that cleave chitin or related polysaccharides. Here, we …