Rolling adhesion on vascular surfaces is the first step in recruiting circulating leukocytes,
hematopoietic progenitors, or platelets to specific organs or to sites of infection or injury …

Interactions of selectins with cell-surface glycoconjugates mediate tethering and rolling
adhesion of leukocytes and platelets on vascular surfaces. Recent studies have helped …

In the past, inflammation has been associated with infections and with the immune system.
But more recent evidence suggests that a much broader range of diseases have telltale …

In inflammation, neutrophils roll along the endothelial wall of postcapillary venules and
sample inflammatory signals. Neutrophil activation is required to generate β2 integrin bonds …

The mechanics of leukocyte (white blood cell; WBC) deformation and adhesion to
endothelial cells (EC) has been investigated using a novel in vitro side-view flow assay. HL …

Flow-enhanced cell adhesion is an unexplained phenomenon that might result from a
transport-dependent increase in on-rates or a force-dependent decrease in off-rates of …

With the recent revolution in Molecular Biology and the deciphering of the Human Genome,
understanding of the building blocks that comprise living systems has advanced rapidly. We …

The mechanics of leukocyte [white blood cell (WBC)] deformation and adhesion to
endothelial cells (EC) in shear flow has been investigated. Experimental data on transient …

A cell-scaled microbead system was used to analyze the force-dependent kinetics of P-
selectin adhesive bonds independent of micromechanical properties of the neutrophil's …

Leukocytes roll on selectins at nearly constant velocities over a wide range of wall shear
stresses. Ligand-coupled microspheres roll faster on selectins and detach quickly as wall …