Altering calcium sensitivity in heart failure: a crossroads of disease etiology and therapeutic innovation
NS Saad, MA Mashali, SJ Repas… - International journal of …, 2023 - mdpi.com
Heart failure (HF) presents a significant clinical challenge, with current treatments mainly
easing symptoms without stopping disease progression. The targeting of calcium (Ca2+) …
easing symptoms without stopping disease progression. The targeting of calcium (Ca2+) …
Coupling of β-adrenergic and Hippo pathway signaling: Implications for heart failure pathophysiology and metabolic therapy
XJ Du, G She, W Wu, XL Deng - Mitochondrion, 2024 - Elsevier
Activation of the sympatho-β-adrenergic receptor (βAR) system is the hallmark of heart
disease with adverse consequences that facilitate the onset and progression of heart failure …
disease with adverse consequences that facilitate the onset and progression of heart failure …
Ion channel trafficking implications in heart failure
JB Reisqs, YS Qu, M Boutjdir - Frontiers in Cardiovascular Medicine, 2024 - frontiersin.org
Heart failure (HF) is recognized as an epidemic in the contemporary world, impacting
around 1%–2% of the adult population and affecting around 6 million Americans. HF …
around 1%–2% of the adult population and affecting around 6 million Americans. HF …