Due to their unique structures and properties, three-dimensional hydrogels and
nanostructured particles have been widely studied and shown a very high potential for …

Site-specific colon drug delivery is a practical approach for the treatment of local diseases of
the colon with several advantages such as rapid onset of action and reduction of the dosage …

Many drugs show promising results in laboratory research but eventually fail clinical trials.
We hypothesize that one main reason for this translational gap is that current cancer models …

Hydrogels (HDG) are materials exhibiting versatile applications in varying fields such as the
pharmaceutical and biomedical industries. However, HDG are prone to inferior chemical …

Inflammatory bowel disease incidence has been constantly rising for the past few decades.
Current therapies attempt to mitigate its symptoms since no cure is established. The most …

Background The overall objective was to prepare a highly accurate nanocarrier system of
mesalamine for the treatment of ulcerative colitis with increased therapeutic efficacy and …

This paper is aimed at developing innovative hybrid nanocomposites, further used as
controlled release systems suited for the therapy of Inflammatory Bowel Diseases (IBDs). To …

Montmorillonite (MMT) is a highly promising material for use in drug delivery due to its high
drug loading capacity and controlled drug release properties. MMT protects drug molecules …

Biomedical research, known as medical research, is conducive to support and promote the
development of knowledge in the field of medicine. Hydrogels have been extensively used …

The release of mesalazine, an anti-inflammatory drug for Crohn's disease, should be
deferred while delivering along the gastrointestinal tract to maximize drug absorption in the …