Cellular signaling networks are the foundation which determines the fate and function of
cells as they respond to various cues and stimuli. The discovery of fluorescent proteins over …

Simple Summary The PTEN phosphatase is a ubiquitously expressed tumor suppressor,
which inhibits the PI3K/AKT pathway in the cell. The PI3K/AKT pathway is considered to be …

Fluorescent proteins are widely used to study molecular and cellular events, yet this
traditionally relies on delivery of excitation light, which can trigger autofluorescence …

Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) is a tumor suppressor
that is frequently down-modulated in human cancer. PTEN inhibits the phosphatidylinositol 3 …

Signal pathways participate in vital biological processes and regulate complex life activities
through protein modifications. Protein modifications in signal pathways are accompanied by …

Phosphatase and tensin homolog (PTEN) is a tumour suppressor that represents one of the
most common targets for genetic defect in human cancer. PTEN controls an array of …

Intravital microscopy represents a more physiologically relevant method for assessing
therapeutic response. However, the movement into an in vivo setting brings with it several …

Mdm2 antagonizes the tumor suppressor p53. Targeting the Mdm2-p53 interaction
represents an attractive approach for the treatment of cancers with functional p53 …

Abstract Bioluminescence Resonance Energy Transfer (BRET) is widely applied to study
protein-protein interactions, as well as increasingly to monitor both ligand binding and …

The Ni foam decorated with ZnO/BiOI core-shell pn junction nanorods was prepared and
employed as an enzyme loading matrix to detect glucose. The detection potential was …