Host–microbiota interactions in immune-mediated diseases
WE Ruff, TM Greiling, MA Kriegel - Nature Reviews Microbiology, 2020 - nature.com
Host–microbiota interactions are fundamental for the development of the immune system.
Drastic changes in modern environments and lifestyles have led to an imbalance of this …
Drastic changes in modern environments and lifestyles have led to an imbalance of this …
The microbiome in autoimmune diseases
F De Luca, Y Shoenfeld - Clinical & Experimental Immunology, 2019 - academic.oup.com
The microbiome is represented by microorganisms which live in a symbiotic way with the
mammalian. Microorganisms have the ability to influence different physiological aspects …
mammalian. Microorganisms have the ability to influence different physiological aspects …
The gut microbiota promotes distal tissue regeneration via RORγ+ regulatory T cell emissaries
Specific microbial signals induce the differentiation of a distinct pool of RORγ+ regulatory T
(Treg) cells crucial for intestinal homeostasis. We discovered highly analogous populations …
(Treg) cells crucial for intestinal homeostasis. We discovered highly analogous populations …
Sjögren syndrome
P Brito-Zerón, C Baldini, H Bootsma… - Nature reviews Disease …, 2016 - nature.com
Sjögren syndrome (SjS) is a systemic autoimmune disease that primarily affects the exocrine
glands (mainly the salivary and lacrimal glands) and results in the severe dryness of …
glands (mainly the salivary and lacrimal glands) and results in the severe dryness of …
Gut microbiome and metabolites in systemic lupus erythematosus: link, mechanisms and intervention
L Zhang, P Qing, H Yang, Y Wu, Y Liu… - Frontiers in …, 2021 - frontiersin.org
Systemic lupus erythematosus (SLE), often considered the prototype of autoimmune
diseases, is characterized by over-activation of the autoimmune system with abnormal …
diseases, is characterized by over-activation of the autoimmune system with abnormal …
[HTML][HTML] Microbiome and anticancer immunosurveillance
Anticancer immune responses can be considered a desirable form of autoimmunity that may
be profoundly shaped by the microbiome. Here, we discuss evidence for the microbiome's …
be profoundly shaped by the microbiome. Here, we discuss evidence for the microbiome's …
Commensal orthologs of the human autoantigen Ro60 as triggers of autoimmunity in lupus
TM Greiling, C Dehner, X Chen, K Hughes… - Science Translational …, 2018 - science.org
The earliest autoantibodies in lupus are directed against the RNA binding autoantigen
Ro60, but the triggers against this evolutionarily conserved antigen remain elusive. We …
Ro60, but the triggers against this evolutionarily conserved antigen remain elusive. We …
Sjogren's syndrome: An update on disease pathogenesis, clinical manifestations and treatment
FB Vivino, VY Bunya… - Clinical …, 2019 - pubmed.ncbi.nlm.nih.gov
Sjogren's syndrome: An update on disease pathogenesis, clinical manifestations and treatment
Sjogren's syndrome: An update on disease pathogenesis, clinical manifestations and treatment …
Sjogren's syndrome: An update on disease pathogenesis, clinical manifestations and treatment …
[HTML][HTML] Shared gut, but distinct oral microbiota composition in primary Sjögren's syndrome and systemic lupus erythematosus
TA van der Meulen, HJM Harmsen, AV Vila… - Journal of …, 2019 - Elsevier
Objective Alterations in the microbiota composition of the gastro-intestinal tract are
suspected to be involved in the etiopathogenesis of two closely related systemic …
suspected to be involved in the etiopathogenesis of two closely related systemic …
[HTML][HTML] Fecal microbiota transplantation broadening its application beyond intestinal disorders
MQ Xu, HL Cao, WQ Wang, S Wang… - World journal of …, 2015 - ncbi.nlm.nih.gov
Intestinal dysbiosis is now known to be a complication in a myriad of diseases. Fecal
microbiota transplantation (FMT), as a microbiota-target therapy, is arguably very effective …
microbiota transplantation (FMT), as a microbiota-target therapy, is arguably very effective …