Host–microbiota interactions are fundamental for the development of the immune system.
Drastic changes in modern environments and lifestyles have led to an imbalance of this …

The microbiome is represented by microorganisms which live in a symbiotic way with the
mammalian. Microorganisms have the ability to influence different physiological aspects …

Specific microbial signals induce the differentiation of a distinct pool of RORγ+ regulatory T
(Treg) cells crucial for intestinal homeostasis. We discovered highly analogous populations …

Sjögren syndrome (SjS) is a systemic autoimmune disease that primarily affects the exocrine
glands (mainly the salivary and lacrimal glands) and results in the severe dryness of …

Systemic lupus erythematosus (SLE), often considered the prototype of autoimmune
diseases, is characterized by over-activation of the autoimmune system with abnormal …

Anticancer immune responses can be considered a desirable form of autoimmunity that may
be profoundly shaped by the microbiome. Here, we discuss evidence for the microbiome's …

The earliest autoantibodies in lupus are directed against the RNA binding autoantigen
Ro60, but the triggers against this evolutionarily conserved antigen remain elusive. We …

Sjogren's syndrome: An update on disease pathogenesis, clinical manifestations and treatment
Sjogren's syndrome: An update on disease pathogenesis, clinical manifestations and treatment …

Objective Alterations in the microbiota composition of the gastro-intestinal tract are
suspected to be involved in the etiopathogenesis of two closely related systemic …

Intestinal dysbiosis is now known to be a complication in a myriad of diseases. Fecal
microbiota transplantation (FMT), as a microbiota-target therapy, is arguably very effective …