Higher criticism for large-scale inference, especially for rare and weak effects

D Donoho, J Jin - 2015 - projecteuclid.org
In modern high-throughput data analysis, researchers perform a large number of statistical
tests, expecting to find perhaps a small fraction of significant effects against a predominantly …

Comprehensive longitudinal microbiome analysis of the chicken cecum reveals a shift from competitive to environmental drivers and a window of opportunity for …

UZ Ijaz, L Sivaloganathan, A McKenna… - Frontiers in …, 2018 - frontiersin.org
Chickens are a key food source for humans yet their microbiome contains bacteria that can
be pathogenic to humans, and indeed potentially to chickens themselves. Campylobacter is …

Integrated physiological, proteomic, and metabolomic analysis of ultra violet (UV) stress responses and adaptation mechanisms in Pinus radiata

J Pascual, MJ Cañal, M Escandon, M Meijon… - Molecular & Cellular …, 2017 - ASBMB
Globally expected changes in environmental conditions, especially the increase of UV
irradiation, necessitate extending our knowledge of the mechanisms mediating tree species …

Phase transitions for high dimensional clustering and related problems

J Jin, ZT Ke, W Wang - 2017 - projecteuclid.org
Supplementary Material for “Phase transitions for high dimensional clustering and related
problems”. Owing to space constraints, some technical proofs and discussion are relegated …

Dengue virus infection alters post-transcriptional modification of microRNAs in the mosquito vector Aedes aegypti

K Etebari, S Osei-Amo, SP Blomberg, S Asgari - Scientific Reports, 2015 - nature.com
Recent discoveries regarding the importance of isomiRs have increased our understanding
of the regulatory complexities of the miRNAome. Observed changes in the miRNA profiles in …

Modeling the dynamics of drought resilience in South-Central United States using a Bayesian Network

VV Mihunov, NSN Lam - Applied geography, 2020 - Elsevier
Droughts impact both the natural and human communities worldwide. Understanding the
complex process underlying community resilience to drought is crucial to coping with the …

Structural covariance of superficial white matter in mild Alzheimer's disease compared to normal aging

C Carmeli, E Fornari, M Jalili, R Meuli… - Brain and …, 2014 - Wiley Online Library
Introduction Interindividual variations in regional structural properties covary across the
brain, thus forming networks that change as a result of aging and accompanying …

FOXN1 forms higher-order nuclear condensates displaced by mutations causing immunodeficiency

IA Rota, AE Handel, S Maio, F Klein, F Dhalla… - Science …, 2021 - science.org
The transcription factor FOXN1 is a master regulator of thymic epithelial cell (TEC)
development and function. Here, we demonstrate that FOXN1 expression is differentially …

Systems biology and in vitro validation identifies family with sequence similarity 129 member A (FAM129A) as an asthma steroid response modulator

MJ McGeachie, GL Clemmer, B Hayete, H Xing… - Journal of Allergy and …, 2018 - Elsevier
Background Variation in response to the most commonly used class of asthma controller
medication, inhaled corticosteroids, presents a serious challenge in asthma management …

Emerging disparities in community resilience to drought hazard in south-central United States

VV Mihunov, NSN Lam, RV Rohli, L Zou - International Journal of Disaster …, 2019 - Elsevier
In search of new insights into the dynamics of hazard resilience, this study assessed the
temporal changes of community resilience to the drought hazard in the south-central US The …