The continuing important role of radionuclide generator systems for nuclear medicine

FF Knapp, S Mirzadeh - European journal of nuclear medicine, 1994 - Springer
In this review, the continuing importance and status of development of radionuclide
generator systems for nuclear medicine are discussed. Radioisotope costs and availability …

Rhenium-188: availability from the 188W/188Re generator and status of current applications

M RA Pillai, A Dash, FF Knapp - Current radiopharmaceuticals, 2012 - ingentaconnect.com
Rhenium-188 is one of the most readily available generator derived and useful
radionuclides for therapy emitting β-particles (2.12 MeV, 71.1% and 1.965 MeV, 25.6%) and …

Coordination compounds in nuclear medicine

S Jurisson, D Berning, W Jia, D Ma - Chemical reviews, 1993 - ACS Publications
Radiopharmaceuticals, drugs containing a radionu-clide, are used routinely in nuclear
medicine depart-ments for the diagnosis of disease and are under investigation for use in …

Chelator combination as therapeutic strategy in mercury and lead poisonings

J Aaseth, OP Ajsuvakova, AV Skalny… - Coordination Chemistry …, 2018 - Elsevier
The chelating thiols dimercaptosuccinate (DMSA) and dimercaptopropane sulfonate
(DMPS) are effective in enhancing urinary excretion of mercury and lead. However …

Therapy with 188Re-Labeled Radiopharmaceuticals: An Overview of Promising Results from Initial Clinical Trials

JM Jeong, JK Chung - Cancer Biotherapy and …, 2003 - liebertpub.com
The development of an in-house 188W/188Re-generator has greatly increased the use of
188Re for treating various diseases. 188Re is of widespread interest due to its attractive …

Pentavalent rhenium-188 dimercaptosuccinic acid for targeted radiotherapy: synthesis and preliminary animal and human studies

PJ Blower, ASK Lam, MJ O'Doherty, AG Kettle… - European journal of …, 1998 - Springer
Pentavalent rhenium-188 dimercaptosuccinic acid [188 Re (V) DMSA] is a β-emitting
analogue of 99m Tc (V) DMSA, a tracer that is taken up in a variety of tumours and bone …

High-yield synthesis of the terminal 188Re≡ N multiple bond from generator-produced [188ReO4]−

A Boschi, C Bolzati, L Uccelli, A Duatti - Nuclear medicine and biology, 2003 - Elsevier
A novel procedure for the high-yield preparation of Re-188 radiopharmaceuticals containing
a terminal Re≡ N multiple bond is described. This method involves the reaction of …

Targeted radionuclide therapy of painful bone metastases: past developments, current status, recent advances and future directions

A Dash, T Das, FFR Knapp - Current medicinal chemistry, 2020 - ingentaconnect.com
Bone pain arising from secondary skeletal malignancy constitutes one of the most common
types of chronic pain among patients with cancer which can lead to rapid deterioration of the …

Rhenium complexes labeled with 186,188Re for nuclear medicine

K Hashimoto, K Yoshihara - … and Rhenium Their Chemistry and Its …, 2005 - Springer
Complexes labeled with 186 Re and 188 Re have been developed for the radiotherapy
treatment of diseases because of the desirable nuclear properties of these radioisotopes …

Technetium-99m chelates as radiopharmaceuticals

WA Volkert, S Jurisson - Technetium and Rhenium their Chemistry and its …, 2005 - Springer
Abstract Technetium-99m (99m Tc) is currently, and will be in the foreseeable future, the
most widely used radionuclide used in virtually all clinical diagnostic Nuclear Medicine …