Lentiviruses are a distinctive genus of retroviruses that cause chronic, persistent infections in
mammals, including humans. The emergence of pandemic HIV type-1 (HIV-1) infection …

Non-human primates are considered to be likely sources of viruses that can infect humans
and thus pose a significant threat to human population. This is well illustrated by some …

Tetherin (Bst2/CD317/HM1. 24) is an interferon-induced antiviral host protein that inhibits
the release of many enveloped viruses by tethering virions to the cell surface. The HIV-1 …

Tetherin, an interferon-inducible membrane protein, inhibits the release of nascent
enveloped viral particles from the surface of infected cells. However, the mechanisms …

Abstract Tetherin (BST2/CD317) has emerged as a key host cell defense molecule,
inhibiting the release and spread of diverse enveloped virions from infected cells. In this …

The interferon-inducible restriction factor tetherin (also known as CD317, BST-2 or HM1. 24)
has emerged as a key component of the antiviral immune response. Initially, tetherin was …

Tetherin is a broadly active antiviral effector that works by tethering nascent enveloped
virions to a host cell membrane, thus preventing their release. In this study, we demonstrate …

Recent studies have uncovered sterile alpha motif and HD domain 1 (SAMHD1) as the
restriction factor that blocks HIV-1 replication in myeloid cells. In contrast to previously …

Bone marrow stromal cell antigen 2 (BST2), also known as CD317, HM1. 24, or tetherin, is a
type II transmembrane glycoprotein. Its expression is induced by IFN-I, and it initiates host …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of
COVID, replicates at intracellular membranes. Bone marrow stromal antigen 2 (BST-2; …