Cell-wall recycling of the gram-negative bacteria and the nexus to antibiotic resistance

DA Dik, JF Fisher, S Mobashery - Chemical reviews, 2018 - ACS Publications
The importance of the cell wall to the viability of the bacterium is underscored by the breadth
of antibiotic structures that act by blocking key enzymes that are tasked with cell-wall …

Constructing and deconstructing the bacterial cell wall

JF Fisher, S Mobashery - Protein science, 2020 - Wiley Online Library
The history of modern medicine cannot be written apart from the history of the antibiotics.
Antibiotics are cytotoxic secondary metabolites that are isolated from Nature. The …

[HTML][HTML] Direct measurement of the in situ decomposition of microbial-derived soil organic matter

Y Hu, Q Zheng, L Noll, S Zhang, W Wanek - Soil Biology and Biochemistry, 2020 - Elsevier
Soil organic matter (SOM) is the dominant reservoir of terrestrial organic carbon and
nitrogen, and microbial necromass represents a primary input to it. However, knowledge of …

Diversity and regulation of intrinsic β-lactamases from non-fermenting and other Gram-negative opportunistic pathogens

C Juan, G Torrens… - FEMS microbiology …, 2017 - academic.oup.com
This review deeply addresses for the first time the diversity, regulation and mechanisms
leading to mutational overexpression of intrinsic β-lactamases from non-fermenting and …

Bacteria's different ways to recycle their own cell wall

C Mayer, RM Kluj, M Muehleck, A Walter… - International Journal of …, 2019 - Elsevier
The ability to recover components of their own cell wall is a common feature of bacteria. This
was initially recognized in the Gram-negative bacterium Escherichia coli, which recycles …

Progress report: Antimicrobial drug discovery in the resistance era

P Shinu, AKA Mouslem, AB Nair, KN Venugopala… - Pharmaceuticals, 2022 - mdpi.com
Antibiotic resistance continues to be a most serious threat to public health. This situation
demands that the scientific community increase their efforts for the discovery of alternative …

Cell-wall recycling and synthesis in Escherichia coli and Pseudomonas aeruginosa – their role in the development of resistance

S Dhar, H Kumari… - Journal of Medical …, 2018 - microbiologyresearch.org
The bacterial cell-wall that forms a protective layer over the inner membrane is called the
murein sacculus–a tightly cross-linked peptidoglycan mesh unique to bacteria. Cell-wall …

Metabolomic insights into the inhibition mechanism of methyl N-methylanthranilate: A novel quorum sensing inhibitor and antibiofilm agent against Pseudomonas …

Y Ma, Q Shi, Q He, G Chen - International Journal of Food Microbiology, 2021 - Elsevier
The quorum sensing (QS) inhibition effect of methyl N-methylanthranilate (MMA) from
Pericarpium Citri Reticulatae Chachiensis against foodborne pathogen Pseudomonas …

Peptidoglycan recycling mediated by an ABC transporter in the plant pathogen Agrobacterium tumefaciens

MC Gilmore, F Cava - Nature Communications, 2022 - nature.com
During growth and division, the bacterial cell wall peptidoglycan (PG) is remodelled,
resulting in the liberation of PG muropeptides which are typically reinternalized and …

Differences in Fosfomycin Resistance Mechanisms between Pseudomonas aeruginosa and Enterobacterales

D Zheng, PJ Bergen, CB Landersdorfer… - Antimicrobial agents …, 2022 - Am Soc Microbiol
Multidrug-resistant (MDR) Pseudomonas aeruginosa presents a serious threat to public
health due to its widespread resistance to numerous antibiotics. P. aeruginosa commonly …