Human and mouse NKG 2D ligands (NKG 2 DL s) are absent or only poorly expressed by
most normal cells but are upregulated by cell stress, hence, alerting the immune system in …

Historically, rheumatic diseases have not received much attention in Africa, particularly in
sub-Saharan Africa, possibly owing to a focus on the overwhelming incidence of infectious …

Ankylosing spondylitis is a common form of inflammatory arthritis predominantly affecting the
spine and pelvis that occurs in approximately 5 out of 1,000 adults of European descent …

The human major histocompatibility complex class I chain-related gene A (MICA) is one of
the genes in the HLA class I region of chromosome 6. Unlike HLA classical class I gene …

An ever growing number of reports on graft rejection and/or failure even with good HLA
matches have highlighted an important role of non-HLA antigens in influencing allograft …

The MHC class I–related chain A (MICA) molecules exist as membrane-bound and soluble
isoforms and are encoded by a polymorphic gene. Their genetic and phenotype …

Abstract Background Axial spondyloarthritis (AxSpA) is a relatively frequent and debilitating
disease, with a prevalence ranging from 0.1 to 2% in the Caucasian population. Current …

The MHC class I chain‐related molecule A (MICA) is a highly polymorphic ligand for the
activating natural killer (NK)‐cell receptor NKG2D. A single nucleotide polymorphism causes …

The major histocompatibility complex (MHC) class I chain-related A (MICA) is the most
polymorphic non-classical MHC class I gene in humans. It encodes a ligand for NKG2D (NK …

Spondyloarthritis (SpA) has been less well studied than rheumatoid arthritis in North Africa,
due to a belief that it is rare and benign in certain populations. The main genetic trait of SpA …