Free radicals: relationship to human diseases and potential therapeutic applications

BL Zaric, MT Macvanin, ER Isenovic - The International Journal of …, 2023 - Elsevier
Reactive species are highly-reactive enzymatically, or non-enzymatically produced
compounds with important roles in physiological and pathophysiological cellular processes …

Circadian control of mitochondria in reactive oxygen species homeostasis

V Mezhnina, OP Ebeigbe, A Poe… - Antioxidants & redox …, 2022 - liebertpub.com
Significance: Mitochondria produce most of the cellular ATP through the process of oxidative
phosphorylation. Energy metabolism in the mitochondria is associated with the production of …

[HTML][HTML] Potential health benefits of curcumin on female reproductive disorders: A review

DAM Kamal, N Salamt, ANM Yusuf, MIAM Kashim… - Nutrients, 2021 - mdpi.com
Curcumin is one of the main polyphenolic compounds in the turmeric rhizome. It possesses
antioxidant, anti-inflammatory, anti-cancer, anti-arthritis, anti-asthmatic, anti-microbial, anti …

[HTML][HTML] The impact of aging on cardio and cerebrovascular diseases

C Izzo, A Carrizzo, A Alfano, N Virtuoso… - International journal of …, 2018 - mdpi.com
A growing number of evidences report that aging represents the major risk factor for the
development of cardio and cerebrovascular diseases. Understanding Aging from a genetic …

Structure-functional implications of longevity protein p66Shc in health and disease

HA Mir, R Ali, U Mushtaq, FA Khanday - Ageing research reviews, 2020 - Elsevier
ShcA (Src homologous-collagen homologue), family of adapter proteins, consists of three
isoforms which integrate and transduce external stimuli to different signaling networks. ShcA …

Vitamin D deficiency: infertility and neurodevelopmental diseases (attention deficit hyperactivity disorder, autism, and schizophrenia)

MJ Berridge - American Journal of Physiology-Cell …, 2018 - journals.physiology.org
The process of development depends on a number of signaling systems that regulates the
progressive sequence of developmental events. Infertility and neurodevelopmental …

Morin attenuates dexamethasone-mediated oxidative stress and atrophy in mouse C2C12 skeletal myotubes

A Ulla, T Uchida, Y Miki, K Sugiura… - Archives of Biochemistry …, 2021 - Elsevier
Glucocorticoids are the drugs most commonly used to manage inflammatory diseases.
However, they are prone to inducing muscle atrophy by increasing muscle proteolysis and …

The roles of mitochondrial dysfunction and reactive oxygen species in aging and senescence

A Zia, T Farkhondeh… - Current Molecular …, 2022 - ingentaconnect.com
The aging process deteriorates organs' function at different levels, causing its progressive
decline to resist stress, damage, and disease. In addition to alterations in metabolic control …

Protective effects of curcumin against sodium arsenite-induced ovarian oxidative injury in a mouse model

XN Wang, CJ Zhang, HL Diao, Y Zhang - Chinese Medical Journal, 2017 - mednexus.org
Background: Excessive reactive oxygen species (ROS) may lead to a number of
reproductive diseases such as polycystic ovary syndrome. This study aimed to establish an …

Endoplasmic reticulum stress signaling in mammalian oocytes and embryos: life in balance

KE Latham - International review of cell and molecular biology, 2015 - Elsevier
Mammalian oocytes and embryos are exquisitely sensitive to a wide range of insults related
to physical stress, chemical exposure, and exposures to adverse maternal nutrition or health …