Translational applications of hydrogels

S Correa, AK Grosskopf, H Lopez Hernandez… - Chemical …, 2021 - ACS Publications
Advances in hydrogel technology have unlocked unique and valuable capabilities that are
being applied to a diverse set of translational applications. Hydrogels perform functions …

Extracellular matrix-based biomaterial scaffolds and the host response

JM Aamodt, DW Grainger - Biomaterials, 2016 - Elsevier
Extracellular matrix (ECM) collectively represents a class of naturally derived proteinaceous
biomaterials purified from harvested organs and tissues with increasing scientific focus and …

Injectable granular hydrogels with multifunctional properties for biomedical applications

JE Mealy, JJ Chung, HH Jeong, D Issadore… - Advanced …, 2018 - Wiley Online Library
Injectable hydrogels are useful for numerous biomedical applications, such as to introduce
therapeutics into tissues or for 3D printing. To expand the complexity of available injectable …

Natural biomaterials for cardiac tissue engineering: a highly biocompatible solution

QA Majid, ATR Fricker, DA Gregory… - Frontiers in …, 2020 - frontiersin.org
Cardiovascular diseases (CVD) constitute a major fraction of the current major global
diseases and lead to about 30% of the deaths, ie, 17.9 million deaths per year. CVD include …

[HTML][HTML] Harnessing the mesenchymal stem cell secretome for the treatment of cardiovascular disease

SH Ranganath, O Levy, MS Inamdar, JM Karp - Cell stem cell, 2012 - cell.com
The broad repertoire of secreted trophic and immunomodulatory cytokines produced by
mesenchymal stem cells (MSCs), generally referred to as the MSC secretome, has …

Engineering cardiac muscle tissue: a maturating field of research

F Weinberger, I Mannhardt, T Eschenhagen - Circulation research, 2017 - Am Heart Assoc
Twenty years after the initial description of a tissue engineered construct, 3-dimensional
human cardiac tissues of different kinds are now generated routinely in many laboratories …

Alginate biomaterial for the treatment of myocardial infarction: progress, translational strategies, and clinical outlook: from ocean algae to patient bedside

E Ruvinov, S Cohen - Advanced drug delivery reviews, 2016 - Elsevier
Alginate biomaterial is widely utilized for tissue engineering and regeneration due to its
biocompatibility, non-thrombogenic nature, mild and physical gelation process, and the …

Injectable and 3D bioprinted polysaccharide hydrogels: from cartilage to osteochondral tissue engineering

J Radhakrishnan, A Subramanian… - …, 2017 - ACS Publications
Biomechanical performance of functional cartilage is executed by the exclusive anisotropic
composition and spatially varying intricate architecture in articulating ends of diarthrodial …

Decellularized extracellular matrix materials for cardiac repair and regeneration

D Bejleri, ME Davis - Advanced healthcare materials, 2019 - Wiley Online Library
Decellularized extracellular matrix (dECM) is a promising biomaterial for repairing
cardiovascular tissue, as dECM most effectively captures the complex array of proteins …

Detachable microneedle patches deliver mesenchymal stromal cell factor-loaded nanoparticles for cardiac repair

S Hu, D Zhu, Z Li, K Cheng - ACS nano, 2022 - ACS Publications
Intramyocardial injection is a direct and efficient approach to deliver therapeutics to the
heart. However, the injected volume must be very limited, and there is injury to the injection …