Right ventricle (RV) dysfunction is the strongest predictor of mortality in pulmonary arterial
hypertension (PAH), but, at present, there are no therapies directly targeting the failing RV …

Cardiovascular disease (CVD) is the leading cause of death globally for men and women.
Premenopausal women have a lower incidence of hypertension and other cardiovascular …

Rationale: Idiopathic pulmonary arterial hypertension (PAH) is a terminal pulmonary
vascular disease characterized by increased pressure, right ventricular failure, and death …

Idiopathic pulmonary arterial hypertension (IPAH) is a rare but fatal disease diagnosed by
right heart catheterisation and the exclusion of other forms of pulmonary arterial …

Background: The ability of the right ventricle (RV) to adapt to an increased pressure
afterload determines survival in patients with pulmonary arterial hypertension. At present …

Cannabidiol (CBD) is a non-intoxicating compound of Cannabis with anti-fibrotic properties.
Pulmonary hypertension (PH) is a disease that can lead to right ventricular (RV) failure and …

Pulmonary arterial hypertension (PAH) is a complex disease of multifactorial origin. While
registries have demonstrated that women are more susceptible to the disease, females with …

Pulmonary arterial hypertension (PAH) is a progressive and fatal disease without a cure.
The exact pathogenic mechanisms of PAH are complex and poorly understood, yet a …

Objective A growing evidence demonstrates that inflammation is a major contributor to the
pathogenesis of pulmonary arterial hypertension (PAH). However, blocking inflammation …

Rationale: Genetic studies suggest that SOX17 (SRY-related HMG-box 17) deficiency
increases pulmonary arterial hypertension (PAH) risk. Objectives: On the basis of …