Methodological consensus on clinical proton MRS of the brain: Review and recommendations

M Wilson, O Andronesi, PB Barker… - Magnetic resonance …, 2019 - Wiley Online Library
Proton MRS (1H MRS) provides noninvasive, quantitative metabolite profiles of tissue and
has been shown to aid the clinical management of several brain diseases. Although most …

Studies of human tumors by MRS: a review

W Negendank - NMR in Biomedicine, 1992 - Wiley Online Library
The literature describing 31P, 1H, 13C, 23Na and 19F MRS in vivo in human cancers is
reviewed. Cancers have typical metabolic characteristics in 31P and 1H MRS including high …

Real-time metabolic imaging

K Golman, R in 't Zandt… - Proceedings of the …, 2006 - National Acad Sciences
The endogenous substance pyruvate is of major importance to maintain energy
homeostasis in the cells and provides a window to several important metabolic processes …

Image-selected in vivo spectroscopy (ISIS). A new technique for spatially selective NMR spectroscopy

RJ Ordidge, A Connelly, JAB Lohman - Journal of Magnetic Resonance …, 1986 - Elsevier
A method of spatial localization is described which is particularly suitable for the in vivo
spectroscopic investigation of biological and medical samples. The technique overcomes …

Molecular imaging using a targeted magnetic resonance hyperpolarized biosensor

L Schröder, TJ Lowery, C Hilty, DE Wemmer, A Pines - Science, 2006 - science.org
A magnetic resonance approach is presented that enables high-sensitivity, high-contrast
molecular imaging by exploiting xenon biosensors. These sensors link xenon atoms to …

1H MR Spectroscopy of the Brain: Absolute Quantification of Metabolites1

JFA Jansen, WH Backes, K Nicolay, ME Kooi - Radiology, 2006 - pubs.rsna.org
Hydrogen 1 (1H) magnetic resonance (MR) spectroscopy enables noninvasive in vivo
quantification of metabolite concentrations in the brain. Currently, metabolite concentrations …

MR spectroscopic imaging: principles and recent advances

S Posse, R Otazo, SR Dager… - Journal of Magnetic …, 2013 - Wiley Online Library
MR spectroscopic imaging (MRSI) has become a valuable tool for quantifying metabolic
abnormalities in human brain, prostate, breast and other organs. It is used in routine clinical …

MR imaging of the breast with rotating delivery of excitation off resonance: clinical experience with pathologic correlation.

SE Harms, DP Flamig, KL Hesley, MD Meiches… - Radiology, 1993 - pubs.rsna.org
An investigative study was undertaken to determine the potential for a new magnetic
resonance (MR) imaging technique, RODEO (rotating delivery of excitation off resonance) …

Spatial mapping of the chemical shift in NMR

P Mansfield - Magnetic Resonance in Medicine, 1984 - Wiley Online Library
In many biological systems, nuclear magnetic resonance chemical‐shift studies of 31P, 13C,
and 1H can be of great value as a means of studying metabolic processes in vivo. This …

Accelerated MR spectroscopic imaging—a review of current and emerging techniques

W Bogner, R Otazo, A Henning - NMR in Biomedicine, 2021 - Wiley Online Library
Over more than 30 years in vivo MR spectroscopic imaging (MRSI) has undergone an
enormous evolution from theoretical concepts in the early 1980s to the robust imaging …