The goal of vaccine-based cancer immunotherapy is to induce a tumor-specific immune
response that ultimately reduces tumor burden. However, the immune system is often …

The expansion of myeloid-derived suppressor cells (MDSCs) is a common feature of cancer,
but its biological roles and molecular mechanism remain unclear. Here, we investigated a …

Nasopharyngeal carcinoma (NPC) is a rare malignancy in most parts of the world, but is one
of the most common cancers in Southeast Asia. Both genetic and environmental factors …

Background Wee1 is a tyrosine kinase regulating S-G2 cell cycle transition through the
inactivating phosphorylation of CDC2. The inhibition of Wee1 kinase by a selective small …

Nasopharyngeal carcinoma (NPC) is an Asian-prevalent head and neck cancer with high
invasiveness. Although several important risk factors for NPC development have been …

Background: Oral squamous cell carcinoma remains a significant worldwide public health
challenge, associated with high morbidity and mortality. Treatment of this type of cancer …

Background The association between expression of cyclooxygenase‐2 (COX‐2), vascular
endothelial growth factor (VEGF), epidermal growth factor receptor (EGFR), and the long …

Current treatment of advanced-stage nasopharyngeal carcinoma (NPC) is not satisfactory.
Targeted therapies offer hope for extending survival. Here, we developed simple, robust …

Introduction An expanding understanding of the importance of angiogenesis in oncology
and the development of numerous angiogenesis inhibitors are driving the search for …

NSAIDs are extensively used worldwide; nonetheless, they are associated with adverse
gastrointestinal (GI) effects. COX-2 inhibitors (coxibs) have been developed to reduce pain …