Key Green Chemistry research areas from a pharmaceutical manufacturers' perspective revisited

MC Bryan, PJ Dunn, D Entwistle, F Gallou… - Green …, 2018 - pubs.rsc.org
In 2007 the members of the ACS Green Chemistry Institute® Pharmaceutical Roundtable
assembled a list of key green chemistry research areas to both identify transformations that …

Brønsted Acid‐Catalysed Dehydrative Substitution Reactions of Alcohols

S Estopiñá‐Durán, JE Taylor - Chemistry–A European Journal, 2021 - Wiley Online Library
The direct, catalytic dehydrative substitution of alcohols is a challenging, yet highly desirable
process in the development of more sustainable approaches to organic chemistry. This …

Redox-neutral organocatalytic Mitsunobu reactions

RH Beddoe, KG Andrews, V Magné, JD Cuthbertson… - Science, 2019 - science.org
Nucleophilic substitution reactions of alcohols are among the most fundamental and
strategically important transformations in organic chemistry. For over half a century, these …

Lewis base catalysis promoted nucleophilic substitutions–recent advances and future directions

PH Huy - European Journal of Organic Chemistry, 2020 - Wiley Online Library
Nucleophilic substitutions (SN) account for the most essential and frequently applied
chemical transformations. SN‐reactions allow forging C–C, C–O, C–N and C–Cl bonds, for …

Intramolecular substitutions of secondary and tertiary alcohols with chirality transfer by an iron (III) catalyst

RA Watile, A Bunrit, J Margalef, S Akkarasamiyo… - Nature …, 2019 - nature.com
Optically pure alcohols are abundant in nature and attractive as feedstock for organic
synthesis but challenging for further transformation using atom efficient and sustainable …

Regioselective Transition Metal-Free Catalytic Ring Opening of 2H-Azirines by Phenols and Naphthols; One-Pot Access to Benzo- and Naphthofurans

A Roy, S Biswas, S Duari, S Maity… - The Journal of …, 2023 - ACS Publications
Benzofuran and naphthofuran derivatives are synthesized from readily available phenols
and naphthols. Regioselective ring openings of 2 H-azirine followed by in situ aromatization …

Fusion of multiple spectra for investigating chemical bonding properties via machine learning

S Guo, J Jiang, H Ren, S Wang - The Journal of Physical …, 2023 - ACS Publications
Chemical bonding properties are crucial to understanding the chemical behavior of
molecules. Spectroscopy is a versatile technical tool to study various microscopic properties …

Ligand‐Free Pd‐Catalyzed Reductive Mizoroki‐Heck Reaction Strategy for the One‐Pot Synthesis of Functionalized Oxygen Heterocycles in Deep Eutectic Solvents

G Dilauro, L Cicco, P Vitale, FM Perna… - European Journal of …, 2023 - Wiley Online Library
Abstract A Deep Eutectic Solvent, choline chloride/glycerol (1: 2 mol mol− 1), proved to be
an effective and sustainable reaction medium to promote telescoped, one‐pot Mizoroki …

Triflic Acid‐Catalyzed Dehydrative Amination of 2‐Arylethanols with Weak N‐Nucleophiles in Hexafluoroisopropanol

M Van Hoof, RJ Mayer, J Moran… - Angewandte Chemie …, 2024 - Wiley Online Library
The catalytic deoxyamination of readily available 2‐arylethanols offers an appealing, simple,
and straightforward means of accessing β‐(hetero) arylethylamines of biological interest …

Organocatalytic Deoxyhalogenation of Alcohols with Inorganic Halides

W Wang, H Wang, R Dai, Y Wang, Z Li, X Yang… - ACS …, 2023 - ACS Publications
Direct substitution of alcohols has been a popular topic in organic chemistry.
Deoxyhalogenation of alcohols represents one of the most important transformations for …