Inorganic phosphate (Pi) plays a critical function in many tissues of the body: for example, as
part of the hydroxyapatite in the skeleton and as a substrate for ATP synthesis. Pi is the main …

The blood-brain barrier (BBB) is a dynamic but solid shield in the cerebral microvascular
system. It plays a pivotal role in maintaining central nervous system (CNS) homeostasis by …

This paper considers estimation and prediction of a high-dimensional linear regression in
the setting of transfer learning where, in addition to observations from the target model …

Primary familial brain calcification (PFBC) is a genetic neurological disease, yet no effective
treatment is currently available. Here, we identified five novel intronic variants in SLC20A2 …

Primary familial brain calcification (PFBC), also known as Fahr's disease, is a rare inherited
disorder characterized by bilateral calcification in the basal ganglia according to …

Brain calcification is a critical aging-associated pathology and can cause multifaceted
neurological symptoms. Cerebral phosphate homeostasis dysregulation, blood-brain barrier …

This systematic MDSGene review covers individuals with confirmed genetic forms of primary
familial brain calcification (PFBC) available in the literature. Data on 516 (47% men) …

Abstract In 2016, the Movement Disorder Society Task Force for the Nomenclature of
Genetic Movement Disorders presented a new system for naming genetically determined …

The blood-brain barrier (BBB) is an essential gatekeeper for the central nervous system and
incidence of neurodevelopmental disorders (NDDs) is higher in infants with a history of …

Primary familial brain calcification (PFBC) is an inherited neurodegenerative disorder mainly
characterized by progressive calcium deposition bilaterally in the brain, accompanied by …