Dysregulations of synaptic vesicle trafficking in schizophrenia

CN Egbujo, D Sinclair, CG Hahn - Current psychiatry reports, 2016 - Springer
Schizophrenia is a serious psychiatric illness which is experienced by about 1% of
individuals worldwide and has a debilitating impact on perception, cognition, and social …

SchizConnect: Mediating neuroimaging databases on schizophrenia and related disorders for large-scale integration

L Wang, KI Alpert, VD Calhoun, DJ Cobia, DB Keator… - Neuroimage, 2016 - Elsevier
Abstract SchizConnect (www. schizconnect. org) is built to address the issues of multiple
data repositories in schizophrenia neuroimaging studies. It includes a level of mediation …

[PDF][PDF] IGF1 deficiency integrates stunted growth and neurodegeneration in Down syndrome

P Araya, KT Kinning, C Coughlan, KP Smith… - Cell reports, 2022 - cell.com
Down syndrome (DS), the genetic condition caused by trisomy 21 (T21), is characterized by
stunted growth, cognitive impairment, and increased risk of diverse neurological conditions …

Neuroimaging intermediate phenotypes of executive control dysfunction in schizophrenia

G Sutcliffe, A Harneit, H Tost… - Biological Psychiatry …, 2016 - Elsevier
Genetic risk for schizophrenia is associated with impairments in the initiation and
performance of executive control of cognition and action. The nature of these impairments …

Belayer: Modeling discrete and continuous spatial variation in gene expression from spatially resolved transcriptomics

C Ma, U Chitra, S Zhang, BJ Raphael - Cell systems, 2022 - cell.com
Spatially resolved transcriptomics (SRT) technologies measure gene expression at known
locations in a tissue slice, enabling the identification of spatially varying genes or cell types …

Presynaptic proteins complexin-I and complexin-II differentially influence cognitive function in early and late stages of Alzheimer's disease

A Ramos-Miguel, K Sawada, AA Jones… - Acta …, 2017 - Springer
Progressive accumulation of Alzheimer's disease-related pathology is associated with
cognitive dysfunction. Differences in cognitive reserve may contribute to individual …

Inter-tissue coexpression network analysis reveals DPP4 as an important gene in heart to blood communication

Q Long, C Argmann, SM Houten, T Huang, S Peng… - Genome medicine, 2016 - Springer
Background Inter-tissue molecular interactions are critical to the function and behavior of
biological systems in multicellular organisms, but systematic studies of interactions between …

Aging differentially alters the transcriptome and landscape of chromatin accessibility in the male and female mouse Hippocampus

JM Achiro, Y Tao, F Gao, CH Lin, M Watanabe… - bioRxiv, 2023 - biorxiv.org
Aging-related memory impairment and pathological memory disorders such as Alzheimer's
disease differ between males and females, and yet little is known about how aging-related …

MIR137 polygenic risk is associated with schizophrenia and affects functional connectivity of the dorsolateral prefrontal cortex

S Liu, A Li, Y Liu, J Li, M Wang, Y Sun, W Qin… - Psychological …, 2020 - cambridge.org
BackgroundGenome-wide association studies (GWAS) have consistently revealed that a
variant of microRNA 137 (MIR137) shows a quite significant association with schizophrenia …

[HTML][HTML] Aging differentially alters the transcriptome and landscape of chromatin accessibility in the male and female mouse hippocampus

JM Achiro, Y Tao, F Gao, CH Lin… - Frontiers in Molecular …, 2024 - ncbi.nlm.nih.gov
Aging-related memory impairment and pathological memory disorders such as Alzheimer's
disease differ between males and females, and yet little is known about how aging-related …