Importance Sickle cell disease (SCD) is an inherited disorder of hemoglobin, characterized
by formation of long chains of hemoglobin when deoxygenated within capillary beds …

Background Sickle cell disease (SCD) is one of the most common inherited diseases
worldwide. It is associated with lifelong morbidity and a reduced life expectancy …

Study objective We provide an updated assessment of trends in sickle cell disease (SCD)–
related mortality, a significant source of mortality in the United States among black persons …

Background: Sickle cell disease (SCD) is a life-limiting inherited hemoglobinopathy that
results in significant complications and affects quality of life. Hematopoietic stem cell …

Sickle cell disease is caused by an abnormality of the β-globin gene and is characterised by
sickling of the red blood cells. Globally, sub-Saharan African countries share the highest …

Sickle cell disease has been largely an invisible global health issue, especially in regions of
high incidence mainly due to lack of awareness among both the local health policy makers …

Allogeneic stem cell transplantation remains the only curative treatment for sickle cell
anemia (SCA), but the place of myeloablative conditioning in the procedure remains to be …

Sickle cell disease (SCD) is a genetic disorder characterised by anaemia and “sickling” of
red blood cells, leading to chronic haemolytic anaemia, vascular injury, and organ …

Sickle cell disease (SCD) is a monogenic disorder that afflicts approximately 100,000
Americans and millions of people worldwide. It is characterized by hemolytic anemia, vaso …

Objective To evaluate the survival of patients with sickle cell disease (SCD) recorded in the
Belgian SCD Registry and to assess the impact of disease‐modifying treatments (DMT) …