As an essential modulator of IgG disposition, the neonatal Fc receptor (FcRn) governs the
pharmacokinetics and functions many therapeutic modalities. In this review, we thoroughly …

New drugs may in some cases need to be tested in paediatric and pregnant patients.
However, it is difficult to recruit such patients and there are many ethical issues around their …

Problem IgG is the only antibody class, that is, actively transferred from the mother to the
fetus across the placenta by an active, neonatal Fc receptor (FcRn) mediated process during …

Probiotics have shown potential for their use in early life. This study aimed to investigate
whether the administration of Lactobacillus fermentum CECT5716 during pregnancy and …

The composition of bioactive factors with immune activity in human breast milk is widely
studied. However, the knowledge on rat milk immune factors during the whole lactation …

The present study aimed to analyze the rat breast milk profile of fatty acids (FA),
immunoglobulins (Ig), microbiota, and their relationship, and to further assess their …

Neonates are born with an immature immune system, which develops during the first stages
of life. This early immaturity is more acute in preterm newborns. The aim of the present study …

Transplacental antibody transfer is crucially important in shaping neonatal immunity.
Recently, prenatal maternal immunization has been employed to boost pathogen-specific …

Одамнинг она сутида иммуннологик фаоллIgи бўлган биологик фаол омилларнинг
таркиби кенг ўрганилган. Бироқ, лактатсия даврининг дингамикасида каламуш сутининг …

The composition of bioactive factors with immune activity in human breast milk is widely
studied. However, the knowledge on rat milk immune factors during the whole lactation …