Consequences of oxidative stress may be beneficial or detrimental in physiological systems.
An organ system's position on the “hormetic curve” is governed by the source and …

The most dramatic feature of life on Earth is our adaptation to the cycle of day and night.
Throughout evolutionary time, almost all living organisms developed a molecular clock …

Deep sedation without tracheal intubation (monitored anaesthesia care) and general
anaesthesia with tracheal intubation are commonly used anaesthesia techniques for …

The adenosine A2b receptor (Adora2b) has been implicated in cardioprotection from
myocardial ischemia. As such, Adora2b was found to be critical in ischemic preconditioning …

Aims Isoflurane may not only accelerate the process of Alzheimer's disease (AD), but
increase the risk of incidence of postoperative cognitive dysfunction (POCD). However, the …

Background: Liver ischemia/reperfusion (IR) injury is characterized by hepatic tissue
damage and an inflammatory response. This is accompanied by the formation and vascular …

The pharmacological conditioning of the heart with anaesthetics, such as volatile
anaesthetics or opioids, is a phenomenon whereby a transient exposure to an anaesthetic …

Background The aim of our study was to test different anesthetic mixtures in order to identify
the most suitable one for a surgical cardiac ischemia-reperfusion model in mice. Methods 1) …

Recent electrophysiological studies have suggested surges in electrical correlates of
consciousness (ie, elevated gamma power and connectivity) after cardiac arrest (CA). This …

Cardiac transplantation demand is on the rise; nevertheless, organ availability is limited due
to a paucity of suitable donors. Organ donation after circulatory death (DCD) is a solution to …