De-escalation strategies of (chemo) radiation for head-and-neck squamous cell cancers—HPV and beyond
A Rühle, AL Grosu, NH Nicolay - Cancers, 2021 - mdpi.com
Simple Summary HPV-related oropharyngeal squamous cell carcinoma patients have a very
good prognosis but are often suffering from long-term treatment-induced toxicities …
good prognosis but are often suffering from long-term treatment-induced toxicities …
Prognostic significance of tumor-infiltrating lymphocytes and macrophages in nasopharyngeal carcinoma: a systematic review and meta-analysis
W Liu, G Chen, C Zhang, X Liao, J Xie, T Liang… - European Archives of …, 2022 - Springer
Purpose Many studies have investigated the prognostic value of tumor-infiltrating
lymphocytes (TILs) and tumor-infiltrating macrophages (TIMs) in patients with …
lymphocytes (TILs) and tumor-infiltrating macrophages (TIMs) in patients with …
Prognostic value of tumor-infiltrating immune cells and immune checkpoints in elderly head-and-neck squamous cell carcinoma patients undergoing definitive (chemo …
A Rühle, J Todorovic, SSK Spohn, E Gkika, C Becker… - Radiation …, 2022 - Springer
Background and purpose Tumor-infiltrating lymphocytes (TILs) are associated with
locoregional control (LRC) in head-and-neck squamous cell carcinoma (HNSCC) patients …
locoregional control (LRC) in head-and-neck squamous cell carcinoma (HNSCC) patients …
18F-FMISO-PET Hypoxia Monitoring for Head-and-Neck Cancer Patients: Radiomics Analyses Predict the Outcome of Chemo-Radiotherapy
M Carles, T Fechter, AL Grosu, A Sörensen… - Cancers, 2021 - mdpi.com
Simple Summary In this study, we monitored FMISO-hypoxia during chemo-radiotherapy
(CRT) in head-and-neck cancer patients and we aimed to develop a radiomics model for …
(CRT) in head-and-neck cancer patients and we aimed to develop a radiomics model for …
Immune-scoring in head and neck squamous cell carcinoma: a scoping review
R Zamani, N Rezaei - Expert Review of Clinical Immunology, 2024 - Taylor & Francis
Introduction Head and neck squamous cell carcinomas (HNSCCs) have an increasing
incidence, high recurrence, and an overall unfavorable prognosis despite numerous …
incidence, high recurrence, and an overall unfavorable prognosis despite numerous …
Review of biomarkers for response to immunotherapy in HNSCC microenvironment
S Chen, Y Yang, S He, M Lian, R Wang… - Frontiers in …, 2023 - frontiersin.org
Head and neck squamous cell carcinoma are one of the most common types of cancer
worldwide. Although a variety of treatment methods such as surgery, radiotherapy …
worldwide. Although a variety of treatment methods such as surgery, radiotherapy …
Transcriptome analysis reveals the prognostic and immune infiltration characteristics of glycolysis and hypoxia in head and neck squamous cell carcinoma
J Liu, J Lu, W Li - BMC cancer, 2022 - Springer
Background This study aims to construct a new prognostic gene signature in survival
prediction and risk stratification for patients with Head and neck squamous cell carcinoma …
prediction and risk stratification for patients with Head and neck squamous cell carcinoma …
Immunohistochemistry-based hypoxia-immune prognostic classifier for head-and-neck cancer patients undergoing chemoradiation–Post-hoc analysis from a …
A Rühle, AL Grosu, N Wiedenmann, R Stoian… - Radiotherapy and …, 2021 - Elsevier
Purpose As both tumor hypoxia and an immunosuppressing tumor microenvironment
hamper the anti-tumor activity of radiotherapy in head-and-neck squamous cell carcinoma …
hamper the anti-tumor activity of radiotherapy in head-and-neck squamous cell carcinoma …
Interleukin-6 as surrogate marker for imaging-based hypoxia dynamics in patients with head-and-neck cancers undergoing definitive chemoradiation—results from a …
Purpose Intratumoral hypoxia increases resistance of head-and-neck squamous cell
carcinoma (HNSCC) to radiotherapy.[18 F] FMISO PET imaging enables noninvasive …
carcinoma (HNSCC) to radiotherapy.[18 F] FMISO PET imaging enables noninvasive …
Y‐Chromosome‐Linked Genes Are Associated With Sex‐Related Head‐Neck Squamous Cell Carcinoma Survival
X Feng, T Zhang, J Chou, HS Patwa… - … –Head and Neck …, 2023 - Wiley Online Library
Objective To define novel gene biomarkers for prognosis of head and neck squamous cell
carcinoma (HNSCC) patients' survival. Study Design Retrospective study. Setting The …
carcinoma (HNSCC) patients' survival. Study Design Retrospective study. Setting The …