Mitochondria are believed to have originated through an ancient endosymbiotic process in
which proteobacteria were captured and co-opted for energy production and cellular …

Mitochondria are the energy center of the cell. They are found in the cell cytoplasm as
dynamic networks where they adapt energy production based on the cell's needs. They are …

As the crucial powerhouse for cell metabolism and tissue survival, the mitochondrion
frequently undergoes morphological or positional changes when responding to various …

Mitochondria play a pivotal role in energy generation and cellular physiological processes.
These organelles are highly dynamic, constantly changing their morphology, cellular …

Mitochondria are fundamental for metabolic homeostasis in all multicellular eukaryotes. In
the nervous system, mitochondria-generated adenosine triphosphate (ATP) is required to …

Kynurenic acid (KynA) is tissue protective in cardiac, cerebral, renal, and retinal ischemia
models, but the mechanism is unknown. KynA can bind to multiple receptors, including the …

The past decade has witnessed an upsurge in studies demonstrating mitochondrial transfer
as one of the emerging mechanisms through which mesenchymal stem cells (MSCs) can …

Misfolded proteins in the central nervous system can induce oxidative damage, which can
contribute to neurodegenerative diseases in the mitochondria. Neurodegenerative patients …

In addition to their intracellular mobility, mitochondria and their components can exist
outside the cells from which they originate. As a result, they are capable of acting on non …

Mammalian genes were long thought to be constrained within somatic cells in most cell
types. This concept was challenged recently when cellular organelles including …