Pathogenicity and virulence of Staphylococcus aureus

GYC Cheung, JS Bae, M Otto - Virulence, 2021 - Taylor & Francis
Staphylococcus aureus is one of the most frequent worldwide causes of morbidity and
mortality due to an infectious agent. This pathogen can cause a wide variety of diseases …

Staphylococcus aureus Secreted Toxins and Extracellular Enzymes

K Tam, VJ Torres - Microbiology spectrum, 2019 - Am Soc Microbiol
Staphylococcus aureus is a formidable pathogen capable of causing infections in different
sites of the body in a variety of vertebrate animals, including humans and livestock. A major …

Staphylococcus aureus pore-forming toxins: The interface of pathogen and host complexity

ES Seilie, JB Wardenburg - Seminars in cell & developmental biology, 2017 - Elsevier
Staphylococcus aureus is a prominent human pathogen capable of infecting a variety of host
species and tissue sites. This versatility stems from the pathogen's ability to secrete diverse …

A CRISPR toolbox to study virus–host interactions

AS Puschnik, K Majzoub, YS Ooi… - Nature Reviews …, 2017 - nature.com
Viruses depend on their hosts to complete their replication cycles; they exploit cellular
receptors for entry and hijack cellular functions to replicate their genome, assemble progeny …

[HTML][HTML] IgE effector mechanisms, in concert with mast cells, contribute to acquired host defense against Staphylococcus aureus

P Starkl, ML Watzenboeck, LM Popov, S Zahalka… - Immunity, 2020 - cell.com
Allergies are considered to represent mal-directed type 2 immune responses against mostly
innocuous exogenous compounds. Immunoglobulin E (IgE) antibodies are a characteristic …

Prevalence and Characterization of PVL-Positive Staphylococcus aureus Isolated from Raw Cow's Milk

A Sadat, RR Shata, AMM Farag, H Ramadan… - Toxins, 2022 - mdpi.com
The present study aimed to investigate the prevalence, antibiotic susceptibility profiles, and
some toxin genes of Panton-Valentine leukocidin (PVL)-positive Staphylococcus aureus (S …

[HTML][HTML] Pleckstrin Homology [PH] domain, structure, mechanism, and contribution to human disease

G Powis, EJ Meuillet, M Indarte, G Booher… - Biomedicine & …, 2023 - Elsevier
The pleckstrin homology [PH] domain is a structural fold found in more than 250 proteins
making it the 11th most common domain in the human proteome. 25% of family members …

Staphylococcus aureus-Associated Skin and Soft Tissue Infections: Anatomical Localization, Epidemiology, Therapy and Potential Prophylaxis

R Olaniyi, C Pozzi, L Grimaldi, F Bagnoli - … aureus: Microbiology, Pathology …, 2017 - Springer
Skin and soft tissue infections (SSTIs) are among the most common infections worldwide.
They range in severity from minor, self-limiting, superficial infections to life-threatening …

Scissor sisters: regulation of ADAM10 by the TspanC8 tetraspanins

AL Matthews, J Szyroka, R Collier… - Biochemical Society …, 2017 - portlandpress.com
A disintegrin and metalloprotease 10 (ADAM10) is a ubiquitously expressed transmembrane
protein which is essential for embryonic development through activation of Notch proteins …

Virulence gene profiles: alpha-hemolysin and clonal diversity in Staphylococcus aureus isolates from bovine clinical mastitis in China

L Zhang, J Gao, HW Barkema, T Ali, G Liu… - BMC veterinary …, 2018 - Springer
Background Staphylococcus aureus, a common cause of bovine mastitis, is known for its
ability to acquire to antimicrobial resistance and to secrete numerous virulence factors that …