Environmental exposures and mechanisms in allergy and asthma development

LB Murrison, EB Brandt, JB Myers… - The Journal of clinical …, 2019 - Am Soc Clin Investig
Environmental exposures interplay with human host factors to promote the development and
progression of allergic diseases. The worldwide prevalence of allergic disease is rising as a …

Environmental pollutants and child health—a review of recent concerns

M Vrijheid, M Casas, M Gascon, D Valvi… - International journal of …, 2016 - Elsevier
In recent years, many new studies have evaluated associations between environmental
pollutants and child health. This review aims to provide a broad summary of this literature …

Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk

N Shrine, AG Izquierdo, J Chen, R Packer, RJ Hall… - Nature …, 2023 - nature.com
Lung-function impairment underlies chronic obstructive pulmonary disease (COPD) and
predicts mortality. In the largest multi-ancestry genome-wide association meta-analysis of …

Lung homeostasis: influence of age, microbes, and the immune system

CM Lloyd, BJ Marsland - Immunity, 2017 - cell.com
Pulmonary immune homeostasis is maintained by a network of tissue-resident cells that
continually monitor the external environment, and in health, instruct tolerance to innocuous …

[HTML][HTML] Dysregulated lipid and fatty acid metabolism link perfluoroalkyl substances exposure and impaired glucose metabolism in young adults

Z Chen, T Yang, DI Walker, DC Thomas, C Qiu… - Environment …, 2020 - Elsevier
Background Per-and polyfluoroalkyl substances (PFASs) exposure is ubiquitous among the
US population and has been linked to adverse health outcomes including cardiometabolic …

[HTML][HTML] Associations of air pollution, obesity and cardiometabolic health in young adults: The Meta-AIR study

JS Kim, Z Chen, TL Alderete, C Toledo-Corral… - Environment …, 2019 - Elsevier
Objective Growing evidence indicates exposure to air pollution contributes to obesity and
cardiometabolic disease risk in children and adults, however studies are lacking in young …

[HTML][HTML] Air pollution exposure is associated with the gut microbiome as revealed by shotgun metagenomic sequencing

F Fouladi, MJ Bailey, WB Patterson, M Sioda… - Environment …, 2020 - Elsevier
Animal work indicates exposure to air pollutants may alter the composition of the gut
microbiota. This study examined relationships between air pollutants and the gut …

[HTML][HTML] What can individuals do to reduce personal health risks from air pollution?

R Laumbach, Q Meng, H Kipen - Journal of thoracic disease, 2015 - ncbi.nlm.nih.gov
In many areas of the world, concentrations of ambient air pollutants exceed levels
associated with increased risk of acute and chronic health problems. While effective policies …

Epigenome-Wide Meta-Analysis of Methylation in Children Related to Prenatal NO2 Air Pollution Exposure

O Gruzieva, CJ Xu, CV Breton… - Environmental …, 2017 - ehp.niehs.nih.gov
Background: Prenatal exposure to air pollution is considered to be associated with adverse
effects on child health. This may partly be mediated by mechanisms related to DNA …

Ambient air pollutant exposures and COVID-19 severity and mortality in a cohort of patients with COVID-19 in Southern California

Z Chen, MA Sidell, BZ Huang, T Chow… - American Journal of …, 2022 - atsjournals.org
Rationale: Ecological studies have shown air pollution associations with coronavirus
disease (COVID-19) outcomes. However, few cohort studies have been conducted …