A role for the N-acetyltransferase 2 (NAT2) genetic polymorphism in cancer risk has been
the subject of numerous studies. Although comprehensive reviews of the NAT2 acetylation …

N-Acetyltransferases (NAT) are key enzymes in the conjugation of certain drugs and other
xenobiotics with an arylamine structure. Polymorphisms in NAT2 have long been recognized …

Resveratrol is a sustainable and versatile bio-derived phenolic compound that has shown
promise as a high glass-transition temperature (T g), flame-resistant building block for …

Human risk and exposure assessments require dosimetry information. Species-specific
tissue dose response will be driven by physiological and biochemical processes. While …

Aromatic amines are organic compounds that contain at least one amino group attached
directly to an aryl moiety. Aromatic amines represent one of the most important classes of …

Recently, studies on circulating microRNAs (miRNAs) as potential biomarkers of drug-
induced liver injury (DILI) have received increasing attention. It has been demonstrated that …

Carvacrol and p‐cymene are sustainable and versatile starting materials for the preparation
of hydrophobic monomers. These molecules can be readily derived from pine resin or …

Toxic industrial chemicals induce liver injury, which is difficult to diagnose without invasive
procedures. Identifying indicators of end organ injury can complement exposure-based …

Introduction: Many different drugs and xenobiotics (chemical compounds foreign to an
organism) can injure the bile duct epithelium and cause inflammatory bile duct diseases …

PMR-15 is a high temperature thermosetting polyimide oligomer widely used in aircraft
engines, rocket casings, bushings, and bearings. Unfortunately, PMR-15 is prepared from …