A unique organelle for studying membrane biochemistry is the mitochondrion whose
functionality depends on a coordinated supply of proteins and lipids. Mitochondria are …

Prohibitin 1 (PHB1) and prohibitin 2 (PHB2) are proteins that are ubiquitously expressed,
and are present in the nucleus, cytosol, and mitochondria. Depending on the cellular …

The removal of unwanted or damaged mitochondria by autophagy, a process called
mitophagy, is essential for key events in development, cellular homeostasis, tumor …

Closely related to studying the function of a protein is the analysis of its three‐dimensional
structure and the identification of interaction sites with its binding partners. An alternative …

Prohibitins comprise an evolutionarily conserved and ubiquitously expressed family of
membrane proteins with poorly described functions. Large assemblies of PHB1 and PHB2 …

Prohibitins comprise an evolutionary conserved and ubiquitously expressed family of
membrane proteins. Various roles in different cellular compartments have been proposed for …

FtsH is a cytoplasmic membrane protein that has N-terminally located transmembrane
segments and a main cytosolic region consisting of AAA-ATPase and Zn2+-metalloprotease …

Prohibitins constitute an evolutionarily conserved and ubiquitously expressed family of
membrane proteins that are essential for cell proliferation and development in higher …

Prohibitins comprise a remarkably conserved protein family in eukaryotic cells with
proposed functions in cell cycle progression, senescence, apoptosis, and the regulation of …

Prohibitins (PHBs) are scaffold proteins that modulate many signaling pathways controlling
cell survival, metabolism, and inflammation. Several drugs that target PHBs have been …