[HTML][HTML] The Japanese clinical practice guidelines for management of sepsis and septic shock 2020 (J-SSCG 2020)

M Egi, H Ogura, T Yatabe, K Atagi, S Inoue, T Iba… - Journal of intensive …, 2021 - Springer
Abstract The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic
Shock 2020 (J-SSCG 2020), a Japanese-specific set of clinical practice guidelines for sepsis …

[HTML][HTML] Ventilator-associated pneumonia in adults: a narrative review

L Papazian, M Klompas, CE Luyt - Intensive care medicine, 2020 - Springer
Ventilator-associated pneumonia (VAP) is one of the most frequent ICU-acquired infections.
Reported incidences vary widely from 5 to 40% depending on the setting and diagnostic …

Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021

L Evans, A Rhodes, W Alhazzani, M Antonelli… - Critical care …, 2021 - journals.lww.com
Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to
infection (1). Sepsis and septic shock are major healthcare problems, impacting millions of …

European resuscitation council and European society of intensive care medicine guidelines 2021: post-resuscitation care

JP Nolan, C Sandroni, BW Böttiger, A Cariou… - Resuscitation, 2021 - Elsevier
Abstract The European Resuscitation Council (ERC) and the European Society of Intensive
Care Medicine (ESICM) have collaborated to produce these post-resuscitation care …

Strategies to prevent ventilator-associated pneumonia, ventilator-associated events, and nonventilator hospital-acquired pneumonia in acute-care hospitals: 2022 …

M Klompas, R Branson, K Cawcutt, M Crist… - Infection Control & …, 2022 - cambridge.org
The purpose of this document is to highlight practical recommendations to assist acute care
hospitals to prioritize and implement strategies to prevent ventilator-associated pneumonia …

Using Bayesian methods to augment the interpretation of critical care trials. An overview of theory and example reanalysis of the alveolar recruitment for acute …

FG Zampieri, JD Casey, M Shankar-Hari… - American journal of …, 2021 - atsjournals.org
Most randomized trials are designed and analyzed using frequentist statistical approaches
such as null hypothesis testing and P values. Conceptually, P values are cumbersome to …

[HTML][HTML] Randomised clinical trials in critical care: past, present and future

A Granholm, W Alhazzani, LPG Derde, DC Angus… - Intensive care …, 2022 - Springer
Randomised clinical trials (RCTs) are the gold standard for providing unbiased evidence of
intervention effects. Here, we provide an overview of the history of RCTs and discuss the …

Acute kidney injury

C Ronco, R Bellomo, JA Kellum - The Lancet, 2019 - thelancet.com
Acute kidney injury (AKI) is defined by a rapid increase in serum creatinine, decrease in
urine output, or both. AKI occurs in approximately 10–15% of patients admitted to hospital …

Effect of stress ulcer prophylaxis with proton pump inhibitors vs histamine-2 receptor blockers on in-hospital mortality among ICU patients receiving invasive …

PJ Young, SM Bagshaw, AB Forbes, AD Nichol… - Jama, 2020 - jamanetwork.com
Importance Proton pump inhibitors (PPIs) or histamine-2 receptor blockers (H 2 RBs) are
often prescribed for patients as stress ulcer prophylaxis drugs in the intensive care unit …

Which multicenter randomized controlled trials in critical care medicine have shown reduced mortality? A systematic review

CA Santacruz, AJ Pereira, E Celis… - Critical care …, 2019 - journals.lww.com
Objectives: To determine which multicenter randomized controlled trials in critically ill
patients have shown that the study intervention was associated with a statistically significant …