The Warburg Effect has emerged as a potential drug target because, in some cancer cell
lines, it is sufficient to subvert it in order to kill cancer cells. It has also been shown that the …

Pancreatic adenocarcinoma (PAAD) is a digestive tumor with extremely high malignancy.
Previous studies have reported that Glucose transporter 1 (GLUT1) contributes to the …

Abstract Irinotecan (CPT-11) is a topoisomerase inhibitor anticancer drug effective against
many human malignancies. Several mechanisms have been proposed for the antitumor …

Background Increased glucose uptake and utilization via aerobic glycolysis are among the
most prominent hallmarks of tumor cell metabolism. Accumulating evidence suggests that …

To find new anti-cancer drug therapies, we wanted to exploit homeostatic vulnerabilities
within Tuberous Sclerosis Complex 2 (TSC2)-deficient cells with mechanistic target of …

We demonstrate sodium pyruvate (NaPy) pre‐treatment as a successful approach for
pressure ulcer (PU) prevention by averting their aetiological origin—cell‐level damage and …

The tumor suppressor protein, p53 responds to cellular stress such as DNA damage,
oncogenic activation and hypoxia by transactivating downstream genes that are responsible …

Purpose: To study the influence of cucurbitacin on malignant biological behavior of
mammary carcinoma cells, and the likely mechanism involved. Methods: Human mammary …

This chapter provides a practical strategy to realize accurate and robust control for 6 DOFs
(degrees of freedom) parallel robots. The presented approach consists in two parts. The first …

This study focused on reprogramming of energy metabolism of cancer cells, since most
cancer and proliferating cells have been shown to display a metabolic shift by displaying …